Branchpoint Binding Protein

Branchpoint Binding Protein (BBP) is an Orem RNA processing factor. The protein complex binds to the branchpoint sequence (BPS) in the pre-mRNA, aiding in splice site recognition.[1]

The role of the protein in yeast cells has been the subject of study, as for other eukaryotic cells.[2] The BPS that the protein binds to in yeast is UACUAAC.[3]

References

"BBP Involved in Splice Site Recognition". Archived from the original on 2010-05-31.
Rymond, B. C. (2010). "The branchpoint binding protein: in and out of the spliceosome cycle". Adv Exp Med Biol. 693: 123–41. doi:10.1007/978-1-4419-7005-3_9. PMID 21189690.
Berglund, J.Andrew; Chua, Katrin; Abovich, Nadja; Reed, Robin; Rosbash, Michael (1997). "The Splicing Factor BBP Interacts Specifically with the Pre-mRNA Branchpoint Sequence UACUAAC". Cell. 89 (5): 781–787. doi:10.1016/S0092-8674(00)80261-5. PMID 9182766. S2CID 10505875.

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[1] "BBP Involved in Splice Site Recognition". Archived from the original on 2010-05-31.

[2] Rymond, B. C. (2010). "The branchpoint binding protein: in and out of the spliceosome cycle". Adv Exp Med Biol. 693: 123–41. doi:10.1007/978-1-4419-7005-3_9. PMID 21189690.

[3] Berglund, J.Andrew; Chua, Katrin; Abovich, Nadja; Reed, Robin; Rosbash, Michael (1997). "The Splicing Factor BBP Interacts Specifically with the Pre-mRNA Branchpoint Sequence UACUAAC". Cell. 89 (5): 781–787. doi:10.1016/S0092-8674(00)80261-5. PMID 9182766. S2CID 10505875.