Brisavirus

Brisavirus (isolate LC KY052047) is a species of Redondoviridae in the genus Torbevirus.[1] Brisa- is from the Spanish word for "Breeze", which refers to their isolation from the human respiratory tract. It was discovered in a throat swab in a male traveler who presented with fever, enlarged adenoids, flushed skin and myalgia after testing negative for other viruses.[2] Brisavirus like other viruses in the Redondoviridae family, are present and putatively replicate in the oro-respiratory tract.[3] They are associated in patients with critical illness and periodontitis.[3]

Brisavirus
Virus classification Edit this classification
(unranked): Virus
Realm: Monodnaviria
Kingdom: Shotokuvirae
Phylum: Cressdnaviricota
Class: Arfiviricetes
Order: Recrevirales
Family: Redondoviridae
Genus: Torbevirus
Species:
Brisavirus

Genome

Brisavirus has a CRESS DNA genome with 3 open reading frames that are inversely oriented that encode for the capsid and Replication-associated protein protein with a small and larger intergenic region.[4] They replicate using rolling-circle replication like other CRESS viruses.[4] By using metagenomic analysis, researchers found that the encoded proteins were most similar to porcine stool-associated circular virus 5 isolate CP33 (PoSCV5).[2][3]

References
  1. taxonomy. "Taxonomy browser (Brisavirus)". www.ncbi.nlm.nih.gov. National Center for Biotechnology Information. Retrieved 2022-03-18.
  2. Cui, Lunbiao; Wu, Binyao; Zhu, Xiaojuan; Guo, Xiling; Ge, Yiyue; Zhao, Kangchen; Qi, Xian; Shi, Zhiyang; Zhu, Fengcai; Sun, Lixin; Zhou, Minghao (2017-11-01). "Identification and genetic characterization of a novel circular single-stranded DNA virus in a human upper respiratory tract sample". Archives of Virology. 162 (11): 3305–3312. doi:10.1007/s00705-017-3481-3. ISSN 1432-8798. PMID 28707271. S2CID 9239411.
  3. Noell, Kristin; Kolls, Jay K. (2019-05-08). "Further Defining the Human Virome using NGS: Identification of Redondoviridae". Cell Host & Microbe. 25 (5): 634–635. doi:10.1016/j.chom.2019.04.010. ISSN 1931-3128. PMC 6849504. PMID 31071291.
  4. "Redondoviridae - Redondoviridae - ssDNA Viruses - ICTV". talk.ictvonline.org. Retrieved 2022-03-17.


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