Bromodifluoroacetyl chloride
Bromodifluoroacetyl chloride is a chemical compound with the formula BrCF2COCl. It has been used as a starting material for the synthesis of (biologically active) α,α-difluoro-γ-lactams[1] and has been used in the synthesis of trifluoromethylated C-nucleosides.[2]
![]() | |
![]() | |
Names | |
---|---|
Preferred IUPAC name
Bromodi(fluoro)acetyl chloride | |
Other names
2-Bromo-2,2-difluoroacetyl chloride 2-Bromo-2,2-difluoro-ethanoyl chloride | |
Identifiers | |
3D model (JSmol) |
|
ChemSpider | |
ECHA InfoCard | 100.197.413 |
EC Number |
|
PubChem CID |
|
CompTox Dashboard (EPA) |
|
| |
| |
Properties | |
C2BrClF2O | |
Molar mass | 193.37 g·mol−1 |
Appearance | liquid |
Boiling point | 50 °C (122 °F; 323 K) |
Hazards | |
GHS labelling: | |
![]() ![]() | |
Danger | |
H226, H314 | |
P210, P233, P240, P241, P242, P243, P260, P264, P280, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P321, P363, P370+P378, P403+P235, P405, P501 | |
Safety data sheet (SDS) | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references |
See also
References
- Nagashima, H.; Isono, Y.; Iwamatsu, S. (2001). "Copper-Catalyzed Cyclization of N-Allylhalodifluoroacetamides: An Efficient Synthesis of α,α-difluoro-γ-lactams". Journal of Organic Chemistry. 66 (1): 315–319. doi:10.1021/jo001187f. PMID 11429918.
- Mamata, C.; Heina, M.; Miethchen, R. (2006). "Fluorinated acyclo-C-nucleoside analogues from glycals in two steps". Carbohydrate Research. 341 (10): 1758–1763. doi:10.1016/j.carres.2006.01.011. PMID 16442508.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.