CAP2
Adenylyl cyclase-associated protein 2 is an enzyme that in humans is encoded by the CAP2 gene.[5][6][7]
| CAP2 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| Aliases | CAP2, CAP, adenylate cyclase-associated protein, 2 (yeast), cyclase associated actin cytoskeleton regulatory protein 2 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 618385 MGI: 1914502 HomoloGene: 101397 GeneCards: CAP2 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Function
This gene was identified by its similarity to the gene for human adenylyl cyclase-associated protein. The function of the protein encoded by this gene is unknown. However, the protein appears to be able to interact with adenylyl cyclase-associated protein and actin.[7]
References
- GRCh38: Ensembl release 89: ENSG00000112186 - Ensembl, May 2017
- GRCm38: Ensembl release 89: ENSMUSG00000021373 - Ensembl, May 2017
- "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- Yu G, Swiston J, Young D (Jun 1994). "Comparison of human CAP and CAP2, homologs of the yeast adenylyl cyclase-associated proteins". Journal of Cell Science. 107 (6): 1671–8. doi:10.1242/jcs.107.6.1671. PMID 7962207.
- Hubberstey A, Yu G, Loewith R, Lakusta C, Young D (Jun 1996). "Mammalian CAP interacts with CAP, CAP2, and actin". Journal of Cellular Biochemistry. 61 (3): 459–66. doi:10.1002/(SICI)1097-4644(19960601)61:3<459::AID-JCB13>3.0.CO;2-E. PMID 8761950. S2CID 46076387.
- "Entrez Gene: CAP2 CAP, adenylate cyclase-associated protein, 2 (yeast)".
External links
- Human CAP2 genome location and CAP2 gene details page in the UCSC Genome Browser.
Further reading
- Shibata R, Mori T, Du W, Chuma M, Gotoh M, Shimazu M, Ueda M, Hirohashi S, Sakamoto M (Sep 2006). "Overexpression of cyclase-associated protein 2 in multistage hepatocarcinogenesis". Clinical Cancer Research. 12 (18): 5363–8. doi:10.1158/1078-0432.CCR-05-2245. PMID 17000669.
- Colland F, Jacq X, Trouplin V, Mougin C, Groizeleau C, Hamburger A, Meil A, Wojcik J, Legrain P, Gauthier JM (Jul 2004). "Functional proteomics mapping of a human signaling pathway". Genome Research. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC 442148. PMID 15231748.
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