PSTPIP1

Proline-serine-threonine phosphatase-interacting protein 1 is an enzyme that in humans is encoded by the PSTPIP1 gene.[5][6]

PSTPIP1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesPSTPIP1, CD2BP1, CD2BP1L, CD2BP1S, H-PIP, PAPAS, PSTPIP, proline-serine-threonine phosphatase interacting protein 1
External IDsOMIM: 606347 MGI: 1321396 HomoloGene: 37867 GeneCards: PSTPIP1
Orthologs
SpeciesHumanMouse
Entrez

9051

19200

Ensembl

ENSG00000140368

ENSMUSG00000032322

UniProt

O43586

P97814

RefSeq (mRNA)

NM_003978
NM_001321135
NM_001321136
NM_001321137

NM_011193

RefSeq (protein)

NP_001308064
NP_001308065
NP_001308066
NP_003969

NP_035323

Location (UCSC)Chr 15: 76.99 – 77.04 MbChr 9: 56 – 56.04 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

PSTPIP1 has been shown to interact with:

See also

References

  1. GRCh38: Ensembl release 89: ENSG00000140368 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000032322 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Li J, Nishizawa K, An W, Hussey RE, Lialios FE, Salgia R, Sunder-Plassmann R, Reinherz EL (February 1999). "A cdc15-like adaptor protein (CD2BP1) interacts with the CD2 cytoplasmic domain and regulates CD2-triggered adhesion". EMBO J. 17 (24): 7320–36. doi:10.1093/emboj/17.24.7320. PMC 1171078. PMID 9857189.
  6. "Entrez Gene: PSTPIP1 proline-serine-threonine phosphatase interacting protein 1".
  7. Cong F, Spencer S, Côté JF, Wu Y, Tremblay ML, Lasky LA, Goff SP (December 2000). "Cytoskeletal protein PSTPIP1 directs the PEST-type protein tyrosine phosphatase to the c-Abl kinase to mediate Abl dephosphorylation". Mol. Cell. 6 (6): 1413–23. doi:10.1016/s1097-2765(00)00138-6. PMID 11163214.
  8. Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
  9. Dowbenko D, Spencer S, Quan C, Lasky LA (January 1998). "Identification of a novel polyproline recognition site in the cytoskeletal associated protein, proline serine threonine phosphatase interacting protein". J. Biol. Chem. 273 (2): 989–96. doi:10.1074/jbc.273.2.989. PMID 9422760.
  10. Spencer S, Dowbenko D, Cheng J, Li W, Brush J, Utzig S, Simanis V, Lasky LA (August 1997). "PSTPIP: a tyrosine phosphorylated cleavage furrow-associated protein that is a substrate for a PEST tyrosine phosphatase". J. Cell Biol. 138 (4): 845–60. doi:10.1083/jcb.138.4.845. PMC 2138048. PMID 9265651.
  11. Wu Y, Spencer SD, Lasky LA (March 1998). "Tyrosine phosphorylation regulates the SH3-mediated binding of the Wiskott–Aldrich syndrome protein to PSTPIP, a cytoskeletal-associated protein". J. Biol. Chem. 273 (10): 5765–70. doi:10.1074/jbc.273.10.5765. PMID 9488710.

Further reading


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