CEACAM16
CEACAM16 is a gene which encodes carcinoembryonic antigen. It is the only carcinoembryotic antigen found in the platypus. [1] The protein is expressed in mammalian outer hair cells, and mutations in this gene are associated with autosomal dominant nonsyndromic deafness.[2][3]
| carcinoembryonic antigen-related cell adhesion molecule 16 | |
|---|---|
| Identifiers | |
| Symbol | CEACAM16 |
| NCBI gene | 388551 |
| HGNC | 31948 |
| RefSeq | XM_371177 |
| Other data | |
| Locus | Chr. 19 q13.31 |
References
- Kammerer, Robert; Rüttiger, Lukas; Riesenberg, Rainer; Schäuble, Constanze; Krupar, Rosemarie; Kamp, Annegret; Sunami, Kishiko; Eisenried, Andreas; Hennenberg, Martin; Grunert, Fritz; Bress, Andreas; Battaglia, Sebastiano; Schrewe, Heinrich; Knipper, Marlies; Schneider, Marlon R.; Zimmermann, Wolfgang (June 2012). "Loss of Mammal-specific Tectorial Membrane Component Carcinoembryonic Antigen Cell Adhesion Molecule 16 (CEACAM16) Leads to Hearing Impairment at Low and High Frequencies". Journal of Biological Chemistry. 287 (26): 21584–21598. doi:10.1074/jbc.M111.320481. Retrieved 15 September 2023.
- Zheng, Jing; Miller, Katharine K.; Yang, Tao; Hildebrand, Michael S.; Shearer, A. Eliot; DeLuca, Adam P.; Scheetz, Todd E.; Drummond, Jennifer; Scherer, Steve E.; Legan, P. Kevin; Goodyear, Richard J.; Richardson, Guy P.; Cheatham, Mary Ann; Smith, Richard J.; Dallos, Peter (8 March 2011). "Carcinoembryonic antigen-related cell adhesion molecule 16 interacts with α-tectorin and is mutated in autosomal dominant hearing loss (DFNA4)". Proceedings of the National Academy of Sciences of the United States of America. 108 (10): 4218–4223. doi:10.1073/pnas.1005842108. ISSN 0027-8424. PMC 3054008. PMID 21368133.
- Hofrichter, Michaela A.H.; Nanda, Indrajit; Gräf, Jens; Schröder, Jörg; Shehata-Dieler, Wafaa; Vona, Barbara; Haaf, Thomas (October 2015). "A Novel de novo Mutation in CEACAM16 Associated with Postlingual Hearing Impairment". Molecular Syndromology. 6 (4): 156–163. doi:10.1159/000439576. ISSN 1661-8769. PMC 4662267. PMID 26648831.
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