CIRBP

Cold-inducible RNA-binding protein is a protein that in humans is encoded by the CIRBP gene.[5][6][7] The cold inducible RNA-binding protein CIRBP plays a critical role in controlling the cellular response upon confronting a variety of cellular stresses, including short wavelength ultraviolet light, hypoxia, and hypothermia.

CIRBP
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCIRBP, CIRP, cold inducible RNA binding protein
External IDsOMIM: 602649 MGI: 893588 HomoloGene: 980 GeneCards: CIRBP
Orthologs
SpeciesHumanMouse
Entrez

1153

12696

Ensembl

ENSG00000099622

ENSMUSG00000045193

UniProt

Q14011
Q53XX5

P60824

RefSeq (mRNA)

NM_001280
NM_001300815
NM_001300829

NM_007705

RefSeq (protein)

NP_001271
NP_001287744
NP_001287758
NP_001271.1

Location (UCSC)Chr 19: 1.26 – 1.27 MbChr 10: 80.17 – 80.17 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

References

  1. GRCh38: Ensembl release 89: ENSG00000099622 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000045193 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Nishiyama H, Higashitsuji H, Yokoi H, Itoh K, Danno S, Matsuda T, Fujita J (Feb 1998). "Cloning and characterization of human CIRP (cold-inducible RNA-binding protein) cDNA and chromosomal assignment of the gene". Gene. 204 (1–2): 115–20. doi:10.1016/S0378-1119(97)00530-1. PMID 9434172.
  6. Nishiyama H, Itoh K, Kaneko Y, Kishishita M, Yoshida O, Fujita J (Jun 1997). "A Glycine-rich RNA-binding Protein Mediating Cold-inducible Suppression of Mammalian Cell Growth". J Cell Biol. 137 (4): 899–908. doi:10.1083/jcb.137.4.899. PMC 2139845. PMID 9151692.
  7. "Entrez Gene: CIRBP cold inducible RNA binding protein".

Further reading


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