CISD2

CDGSH iron sulfur domain 2 is a protein that in humans is encoded by the CISD2 gene.[5]

CISD2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCISD2, ERIS, Miner1, NAF-1, WFS2, ZCD2, CDGSH iron sulfur domain 2
External IDsOMIM: 611507 MGI: 1914256 HomoloGene: 36436 GeneCards: CISD2
Orthologs
SpeciesHumanMouse
Entrez

493856

67006

Ensembl

ENSG00000145354

ENSMUSG00000028165

UniProt

Q8N5K1

Q9CQB5

RefSeq (mRNA)

NM_001008388

NM_025902

RefSeq (protein)

NP_001008389

NP_080178

Location (UCSC)Chr 4: 102.87 – 102.89 MbChr 3: 135.11 – 135.13 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

The protein encoded by this gene is a zinc finger protein that localizes to the endoplasmic reticulum. The encoded protein binds an iron/sulfur cluster and may be involved in calcium homeostasis. Defects in this gene are a cause of Wolfram syndrome 2. [provided by RefSeq, Mar 2011].

See also

References

  1. GRCh38: Ensembl release 89: ENSG00000145354 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000028165 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "CISD2 CDGSH iron sulfur domain 2 [ Homo sapiens (human) ]". National Center for Biotechnology Information. Retrieved 2018-06-04.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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