CLTB

Clathrin, light chain B is a protein in humans that is encoded by the CLTB gene.[5]

CLTB
Identifiers
AliasesCLTB, LCB, clathrin light chain B
External IDsOMIM: 118970 MGI: 1921575 HomoloGene: 37532 GeneCards: CLTB
Orthologs
SpeciesHumanMouse
Entrez

1212

74325

Ensembl

ENSG00000175416

ENSMUSG00000047547

UniProt

P09497

Q6IRU5

RefSeq (mRNA)

NM_001834
NM_007097
NM_001364126
NM_001364127

NM_028870
NM_001347512

RefSeq (protein)

NP_001825
NP_009028
NP_001351055
NP_001351056
NP_001825.1

NP_001334441
NP_083146

Location (UCSC)Chr 5: 176.39 – 176.42 MbChr 13: 54.74 – 54.76 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and coated vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008].

References

  1. GRCh38: Ensembl release 89: ENSG00000175416 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000047547 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: Clathrin, light chain B". Retrieved 2013-06-05.

Further reading


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