COQ3

COQ3, also known as ubiquinone biosynthesis O-methyltransferase, mitochondrial is an enzyme that in humans is encoded by the COQ3 gene.

COQ3
Identifiers
Aliases	COQ3, DHHBMT, DHHBMTASE, UG0215E05, bA9819.1, coenzyme Q3, methyltransferase
External IDs	OMIM: 605196 MGI: 101813 HomoloGene: 9683 GeneCards: COQ3
EC number	2.1.1.114
Gene location (Human) Chr. Chromosome 6 (human)[1] Band 6q16.2 Start 99,369,401 bp[1] End 99,394,195 bp[1]
Gene location (Mouse) Chr. Chromosome 4 (mouse)[2] Band 4 A3|4 9.11 cM Start 21,879,673 bp[2] End 21,912,162 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in biceps brachii right ventricle vastus lateralis muscle left ventricle triceps brachii muscle deltoid muscle gastrocnemius muscle middle temporal gyrus cerebellar hemisphere Brodmann area 9 Top expressed in soleus muscle intercostal muscle interventricular septum vastus lateralis muscle right ventricle digastric muscle sternocleidomastoid muscle tibialis anterior muscle masseter muscle thoracic diaphragm More reference expression data BioGPS n/a
Gene ontology Molecular function methyltransferase activity transferase activity hexaprenyldihydroxybenzoate methyltransferase activity 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity O-methyltransferase activity 3-demethylubiquinone-9 3-O-methyltransferase activity decaprenyldihydroxybenzoate methyltransferase activity 3-demethylubiquinol-10 3-O-methyltransferase activity protein binding Cellular component mitochondrial inner membrane mitochondrial matrix mitochondrion membrane extrinsic component of mitochondrial inner membrane Biological process methylation ubiquinone biosynthetic process glycerol metabolic process regulation of ubiquinone biosynthetic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 51805 230027 Ensembl ENSG00000132423 ENSMUSG00000028247 UniProt Q9NZJ6 Q8BMS4 RefSeq (mRNA) NM_017421 NM_172687 NM_001356348 RefSeq (protein) NP_059117 NP_766275 NP_001343277 Location (UCSC) Chr 6: 99.37 – 99.39 Mb Chr 4: 21.88 – 21.91 Mb PubMed search [3] [4]
Wikidata
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