Carboxypeptidase A1

Carboxypeptidase A1 is an enzyme that in humans is encoded by the CPA1 gene.[5]

CPA1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCPA1, CPA, carboxypeptidase A1
External IDsOMIM: 114850 MGI: 88478 HomoloGene: 55609 GeneCards: CPA1
Orthologs
SpeciesHumanMouse
Entrez

1357

109697

Ensembl

ENSG00000091704

ENSMUSG00000054446

UniProt

P15085

Q7TPZ8

RefSeq (mRNA)

NM_001868

NM_025350

RefSeq (protein)

NP_001859

NP_079626

Location (UCSC)Chr 7: 130.38 – 130.39 MbChr 6: 30.64 – 30.65 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Three different forms of human pancreatic procarboxypeptidase A have been isolated. The A1 and A2 forms are monomeric proteins with different biochemical properties. Carboxypeptidase A1 is a monomeric pancreatic exopeptidase. It is involved in zymogen inhibition.[5]

References

  1. GRCh38: Ensembl release 89: ENSG00000091704 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000054446 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: CPA1 carboxypeptidase A1 (pancreatic)".

Further reading

  • The MEROPS online database for peptidases and their inhibitors: M14.001
  • Overview of all the structural information available in the PDB for UniProt: P15085 (Carboxypeptidase A1) at the PDBe-KB.


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