CTDSP1

Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 is an enzyme that in humans is encoded by the CTDSP1 gene.[5][6][7]

CTDSP1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCTDSP1, NIF3, NLI-IF, NLIIF, SCP1, CTD small phosphatase 1
External IDsOMIM: 605323 MGI: 2654470 HomoloGene: 100834 GeneCards: CTDSP1
Orthologs
SpeciesHumanMouse
Entrez

58190

227292

Ensembl

ENSG00000144579

ENSMUSG00000026176

UniProt

Q9GZU7

P58466

RefSeq (mRNA)

NM_001206878
NM_001206879
NM_021198
NM_182642

NM_153088

RefSeq (protein)

NP_001193807
NP_067021
NP_872580

NP_694728

Location (UCSC)Chr 2: 218.4 – 218.41 MbChr 1: 74.43 – 74.44 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

CTDSP1 has been shown to interact with SNAI1.[8]

References

  1. GRCh38: Ensembl release 89: ENSG00000144579 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000026176 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Ma X, Wright J, Dou S, Olsen P, Teeter L, Adams G, Graviss E (Apr 2002). "Ethnic divergence and linkage disequilibrium of novel SNPs in the human NLI-IF gene: evidence of human origin and lack of association with tuberculosis susceptibility". Journal of Human Genetics. 47 (3): 140–5. doi:10.1007/s100380200016. PMID 11950066.
  6. Yeo M, Lin PS, Dahmus ME, Gill GN (July 2003). "A novel RNA polymerase II C-terminal domain phosphatase that preferentially dephosphorylates serine 5". The Journal of Biological Chemistry. 278 (28): 26078–85. doi:10.1074/jbc.M301791200. PMID 12721286.
  7. "Entrez Gene: CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1".
  8. Wu Y, Evers BM, Zhou BP (January 2009). "Small C-terminal domain phosphatase enhances snail activity through dephosphorylation". The Journal of Biological Chemistry. 284 (1): 640–8. doi:10.1074/jbc.M806916200. PMC 2610500. PMID 19004823.

Further reading

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