Chymotrypsin-C

Chymotrypsin C, also known as caldecrin or elastase 4, is an enzyme that in humans is encoded by the CTRC gene.[5][6]

CTRC
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCTRC, CLCR, ELA4, chymotrypsin C
External IDsOMIM: 601405 MGI: 1923951 HomoloGene: 21422 GeneCards: CTRC
Orthologs
SpeciesHumanMouse
Entrez

11330

76701

Ensembl

ENSG00000162438

ENSMUSG00000062478

UniProt

Q99895

Q3SYP2

RefSeq (mRNA)

NM_007272

NM_001033875

RefSeq (protein)

NP_009203

NP_001029047

Location (UCSC)Chr 1: 15.44 – 15.45 MbChr 4: 141.57 – 141.57 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

Chymotrypsin C is a member of the peptidase S1 family. The encoded protein is a serum calcium-decreasing factor that has chymotrypsin-like protease activity.[5]

References

  1. GRCh38: Ensembl release 89: ENSG00000162438 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000062478 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: chymotrypsin C (caldecrin)".
  6. Tomomura A, Akiyama M, Itoh H, Yoshino I, Tomomura M, Nishii Y, Noikura T, Saheki T (May 1996). "Molecular cloning and expression of human caldecrin". FEBS Lett. 386 (1): 26–8. doi:10.1016/0014-5793(96)00377-8. PMID 8635596.

Further reading


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