Caffeoylquinic acid

Caffeoylquinic acids (CQA) are compounds composed of a quinic acid core, acylated with one or more caffeoyl groups. There is a positive correlation between the number of caffeoyl groups bound to quinic acid and the rate of ATP production.[1] Compounds of this class include:

  • Chlorogenic acid (3-O-caffeoylquinic acid or 3-CQA)
  • 4-O-caffeoylquinic acid (crypto-chlorogenic acid or 4-CQA)
  • 5-O-caffeoylquinic acid (neo-chlorogenic acid or 5-CQA)
  • 1,5-diCQA
  • 3,4-diCQA
  • 3,5-diCQA
  • 4,5-diCQA

References
  1. Miyamae, Y.; Kurisu, M.; Han, J.; Isoda, H.; Shigemori, H. (2011). "Structure–Activity Relationship of Caffeoylquinic Acids on the Accelerating Activity on ATP Production". Chemical and Pharmaceutical Bulletin. 59 (4): 502–507. PMID 21467684.
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