Cartwheel pattern

A cartwheel pattern pattern is a histopathologic architectural pattern. Microscopically, cartwheel arrangements appear to have center points that radiate cells or connective tissue outward. Cartwheel patterns may be irregular and, at lower magnification, can cause tissue to appear tangled into clumps.[1]

Cartwheel pattern. This is a case of dermatofibrosarcoma protuberans from skin and soft tissue in the abdominal area. HE stain.

Skin tumors that can be classified as "storiform," having spindle cells with elongated nuclei radiating from a center point, are mainly:[2]

Fibrous histiocytoma (dermatofibroma)
Soft tissue perineurioma
Dermatofibrosarcoma protuberans

References

Stone, John H.; Zen, Yoh; Deshpande, Vikram (2012). "IgG4-Related Disease". The New England Journal of Medicine. 366: 539–551. doi:10.1056/NEJMra1104650.
Choi, Joon Hyuk; Ro, Jae Y. (2018). "Cutaneous Spindle Cell Neoplasms: Pattern-Based Diagnostic Approach". Archives of Pathology & Laboratory Medicine. 142 (8): 958–972. doi:10.5858/arpa.2018-0112-RA. ISSN 0003-9985. PMID 30040457.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

[stone-1] Stone, John H.; Zen, Yoh; Deshpande, Vikram (2012). "IgG4-Related Disease". The New England Journal of Medicine. 366: 539–551. doi:10.1056/NEJMra1104650.

[ChoiRo2018-2] Choi, Joon Hyuk; Ro, Jae Y. (2018). "Cutaneous Spindle Cell Neoplasms: Pattern-Based Diagnostic Approach". Archives of Pathology & Laboratory Medicine. 142 (8): 958–972. doi:10.5858/arpa.2018-0112-RA. ISSN 0003-9985. PMID 30040457.