Cetomacrogol 1000

Cetomacrogol 1000 is the tradename for polyethylene glycol hexadecyl ether, which is nonionic surfactant produced by the ethoxylation of cetyl alcohol to give a material with the general formula HO(C2H4O)nC16H33. Several grades of this material are available depending on the level of ethoxylation performed, with repeat units (n) of polyethylene glycol varying between 2 and 20. Commercially it can be known as Brij 58 (when n=20) or Brij 56 (when n=10). Brij is a trademark of Croda International.

Cetomacrogol 1000

The structure of polyethylene glycol hexadecyl ether with 20 polyethylene glycol units
Names
IUPAC name
α-Hexadecyl-ω-hydroxypoly(oxyethylene)
Other names
polyoxyethylene cetyl ether
Brij 58
Brij 56
Brij 52
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.105.524
EC Number
  • 500-014-1
UNII
  • InChI=1S/C56H114O21/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-17-58-19-21-60-23-25-62-27-29-64-31-33-66-35-37-68-39-41-70-43-45-72-47-49-74-51-53-76-55-56-77-54-52-75-50-48-73-46-44-71-42-40-69-38-36-67-34-32-65-30-28-63-26-24-61-22-20-59-18-16-57/h57H,2-56H2,1H3
    Key: NLMKTBGFQGKQEV-UHFFFAOYSA-N
  • CCCCCCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO
Hazards
GHS labelling:
GHS07: Exclamation mark
Warning
H302, H315
P264, P270, P280, P301+P312, P302+P352, P321, P330, P332+P313, P362, P501
Safety data sheet (SDS) MSDS
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

It is used as a solubilizer and emulsifying agent in foods, cosmetics, and pharmaceuticals, often as an ointment base. It is used as an oil in water (O/W) emulsifier for creams/lotions, and a wetting agent.

See also
  • Isoceteth-20 - a similar material made using iso-cetyl alcohol

References
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