Charles N. Serhan

Charles Nicholas Serhan is the Simon Gelman Professor of Anaesthesia (Biochemistry and Molecular Pharmacology) at Harvard Medical School and a Professor of Oral Medicine, Infection and Immunity at Harvard School of Dental Medicine.[1] Serhan is the Director of the Center for Experimental Therapeutics and Reperfusion Injury at Brigham and Women's Hospital.[1]

Education

Serhan completed his Bachelor of Science in Biochemistry at State University of New York at Stony Brook in 1978.[2] In 1982, Serhan earned a doctorate in Experimental Pathology and Medical Sciences from New York University School of Medicine.[2] Following his graduation, Serhan began a postdoctoral fellowship at the Karolinska Institute in Stockholm, Sweden under the mentorship of Bengt Samuelsson.[3] Serhan has also received honorary degrees from Harvard University,[1] University College Dublin,[4] and Queen Mary College, University of London.[5]

Career

The focus of Serhan's research are Specialized Pro-Resolving Mediators (SPMs), which are "inflammation-fighting molecules in the body derived from essential fatty acids".[6] While working with Mats Hamberg and Bengt Samuelsson at the Karolinska Institute, Serhan helped discover lipoxin[7] the first of the SPMs to be elucidated.[8] Since this initial discovery, Serhan has identified additional mediators including Resolvins, Maresins, and Protectins.[9]

Serhan became a faculty member at Harvard Medical School in 1987[3] and the Director of the Center for Experimental Therapeutics and Reperfusion Injury at Brigham and Women's Hospital (CET&RI).[1] The CET&RI's mission is: "To identify novel mediators, pathways, and their cellular receptors and targets critical in promoting resolution of inflammation and reperfusion tissue injury and establish their relation to human disease".[10]

Awards and honors

Serhan was awarded the John Vane Medal from The William Harvey Research Institute in 2008.[11] In 2016, he received the Ross Prize in Molecular Medicine.[12] He was awarded the International Eicosanoid Research Foundation's 2017 Lifetime Achievement Award.[13] Serhan was the American Society for Investigative Pathology (ASIP) Rous-Whipple Award recipient in 2018[14] and became an Honorary Life Member of the Society for Leukocyte Biology in 2019.[15] In 2022, Serhan delivered the Hans L. Falk Memorial Lecture at the National Institute of Environmental Health Sciences.[16]

References
  1. "Prof. Charles Serhan, PhD, Research - Brigham and Women's Hospital". www.brighamandwomens.org. Retrieved 2022-12-27.
  2. "Charles Serhan | Harvard Medical School - Academia.edu". hms-harvard.academia.edu. Retrieved 2022-12-27.
  3. "Charles N. Serhan, Ph.D." www.science.org. Retrieved 2022-12-27.
  4. "Charles Serhan - UCD President's Office". www.ucd.ie. Retrieved 2022-12-27.
  5. "Fellows - Queen Mary University of London". www.qmul.ac.uk. Retrieved 2022-12-27.
  6. Communication, Brigham Office of Strategic (2021-03-11). "Your Food, Your Genes, and COVID-19: Q&A with Charles N. Serhan". Brigham Clinical & Research News. Retrieved 2022-12-27.
  7. Serhan, C N; Hamberg, M; Samuelsson, B (1984). "Lipoxins: novel series of biologically active compounds formed from arachidonic acid in human leukocytes". Proc Natl Acad Sci USA. 81 (17): 5335–5339. Bibcode:1984PNAS...81.5335S. doi:10.1073/pnas.81.17.5335. PMC 391698. PMID 6089195.
  8. "The end of inflammation? New approach could treat dozens of diseases". National Geographic. 2022-03-04. Retrieved 2022-12-27.
  9. Research Features (2017-06-19). "Lipid mediators put an end to inflammation". Research Features. Retrieved 2022-12-27.
  10. "Serhan Lab – Brigham and Women's Hospital". Retrieved 2022-12-27.
  11. "Award Winners - The William Harvey Research Institute - Faculty of Medicine and Dentistry". www.qmul.ac.uk. Retrieved 2022-12-27.
  12. Gentile, Marie (2016-06-02). "Inflammation Researcher to Receive 2016 Ross Prize". The New York Academy of Sciences. Retrieved 2022-12-27.
  13. "ACHIEVEMENT AWARD – Bioactive Lipids in Cancer, Inflammation and Related Diseases". Retrieved 2022-12-27.
  14. "Dr. Charles N. Serhan Receives the ASIP 2018 Rous-Whipple Award". www.newswise.com. Retrieved 2022-12-27.
  15. "Honorary Life Members". www.leukocytebiology.org. Retrieved 2022-12-27.
  16. "Falk Memorial Lecture focuses on how inflammation ends (Environmental Factor, April 2022)". National Institute of Environmental Health Sciences. Retrieved 2022-12-27.

Serhan Lab Website

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