Charlotte Deane

Charlotte Mary Deane MBE (born 1975) is an English Professor of Structural Bioinformatics and the former Head of the Department of Statistics at the University of Oxford.

Charlotte Deane
Born6 May 1975 Edit this on Wikidata (age 48)
Alma mater
Websitehttp://www.stats.ox.ac.uk/~deane/, http://opig.stats.ox.ac.uk Edit this on Wikidata
Academic career
FieldsStructural biology, bioinformatics Edit this on Wikidata
Institutions
ThesisProtein structure prediction: amino acid propensities and comparative modelling
Doctoral advisorTom Blundell
Academic advisorGraham Richards, David Eisenberg
Doctoral studentsAnna Lewis, Sumeet Agarwal, Florian Klimm

Early life and education

Charlotte Deane was born in May 1975.[1] She completed her undergraduate education at University College, Oxford studying chemistry, completing her final year project in Graham Richards' group.[2][1] She then went to the University of Cambridge to study structural bioinformatics supervised by Tom Blundell.[3] In 2000 she published her thesis entitled "Protein structure prediction: amino acid propensities and comparative modelling".[4]

Career and research

Deane moved to UCLA where she stayed for two years supervised by David Eisenberg as a Wellcome Trust Research Fellow, before moving back to Oxford.[3][5]

Her research is focused on the prediction of protein structures, particularly antibodies. Her research group, Oxford Protein Informatics Group (OPIG), created a database of antibody structures called SABDab[6] and a server for prediction of antibody structures called SAbPred.[7][8][9]

In addition, Deane's research is focused on immunoinformatics, biological networks and small molecules.[10]

Honours and awards

In 2007 and 2008, Deane was awarded an Oxford Teaching Award.[11][12] In 2002 she was elected as fellow of Kellogg College and University Lecturer.[13] In 2010 she was elected as Professor of Structural Bioinformatics and in October 2015 she was appointed Head of the Department of Statistics at the University of Oxford.[14][15] She is the first female Head of department since the department was created in 1988.

In 2014, Deane became Associate Head of the Mathematical Physical and Life Sciences (MPLS) division and the Deputy Head of the Division in 2018.[16][17]

Deane became a fellow of St Anne's College in 2015.[18]

In September 2019, Deane was appointed Deputy Executive Chair of the Engineering and Physical Sciences Research Council (EPSRC).[19]

As of January 2022, Deane joined Exscientia as Chief Scientist of Biologics AI.[20]

She was appointed Member of the Order of the British Empire (MBE) in the 2022 Birthday Honours for services to Covid-19 research.[21]

References
  1. "Charlotte Deane". 2001-05-03. Archived from the original on 2001-05-03. Retrieved 2018-02-17.
  2. Oxford Statistics (2016-08-03), Exciting Scientists: Charlotte Deane Interview with Winton Capital, retrieved 2018-02-17
  3. "Charlotte Deane | 2020 Science". 2020science.net. Retrieved 2018-02-17.
  4. Deane, Charlotte. "Thesis". idiscover.lib.cam.ac.uk. Retrieved 2018-02-17.
  5. "Former Lab Members | David Eisenberg's Lab". eisenberglab.mbi.ucla.edu. Retrieved 2018-02-17.
  6. "SAbDab - Structural Antibody Database". opig.stats.ox.ac.uk.
  7. "SAbPred - Structural Antibody Prediction Server". opig.stats.ox.ac.uk.
  8. Dunbar, James; Krawczyk, Konrad; Leem, Jinwoo; Baker, Terry; Fuchs, Angelika; Georges, Guy; Shi, Jiye; Deane, Charlotte M. (2014-01-01). "SAbDab: the structural antibody database". Nucleic Acids Research. 42 (D1): D1140–D1146. doi:10.1093/nar/gkt1043. ISSN 0305-1048. PMC 3965125. PMID 24214988.
  9. Dunbar, James; Krawczyk, Konrad; Leem, Jinwoo; Marks, Claire; Nowak, Jaroslaw; Regep, Cristian; Georges, Guy; Kelm, Sebastian; Popovic, Bojana (2016-07-08). "SAbPred: a structure-based antibody prediction server". Nucleic Acids Research. 44 (W1): W474–W478. doi:10.1093/nar/gkw361. ISSN 0305-1048. PMC 4987913. PMID 27131379.
  10. "Charlotte Deane - Research Interests". Charlotte Deane.
  11. "Oxford Teaching Awards 2007–2008" (PDF). GAZETTE. 2008-10-22. Archived from the original (PDF) on 2018-02-24. Retrieved 2018-02-17.
  12. "Oxford Teaching Awards 2006–2007" (PDF). GAZETTE. 2007-11-28. Archived from the original (PDF) on 2018-02-24. Retrieved 2018-02-17.
  13. "Oxf. Univ. Gazette, 26 September 2002: Examinations and Boards". ox.ac.uk. Archived from the original on 27 February 2018. Retrieved 2018-02-17.
  14. Oxford, University of. "Notices, Oxford University Gazette". ox.ac.uk. Archived from the original on 2015-12-22. Retrieved 2018-02-17.
  15. Statistics, Oxford (1 Oct 2015). "Congratulations to Prof Charlotte Deane taking over as Head of Dept today". @oxfordstats. Retrieved 2018-02-17.
  16. "Charlotte Deane - Positions and Employment". Charlotte Deane.
  17. "MPLS Awards Announced by Charlotte Deane, Deputy Head of Division".
  18. "St Anne's Fellows" (PDF). St Anne's College. 2015.
  19. "EPSRC appoints Professor Charlotte Deane as Deputy Executive Chair — Mathematical, Physical and Life Sciences Division". www.mpls.ox.ac.uk. Retrieved 2019-09-11.
  20. "Professor Charlotte Deane Joins Exscientia as Chief Scientist of Biologics AI". Exscientia. 2022-01-19. Retrieved 2022-01-27.
  21. "No. 63714". The London Gazette (Supplement). 1 June 2022. p. B19.
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