Chitin deacetylase
In enzymology, a chitin deacetylase (EC 3.5.1.41) is an enzyme that catalyzes the chemical reaction
- chitin + H2O chitosan + acetate
| chitin deacetylase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.5.1.41 | ||||||||
| CAS no. | 56379-60-3 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are chitin and H2O, whereas its two products are chitosan and acetate.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is chitin amidohydrolase. This enzyme participates in aminosugars metabolism.
Structural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 2IW0.
References
- Araki Y, Ito E (1974). "A pathway of chitosan formation in Mucor rouxii: enzymatic deacetylation of chitin". Biochem. Biophys. Res. Commun. 56 (3): 669–75. doi:10.1016/0006-291X(74)90657-3. PMID 4826874.
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