Cholamine chloride hydrochloride

Cholamine chloride hydrochloride is one of Good's buffers with a pH in the physiological range. Its pKa at 20°C is 7.10, making it useful in cell culture work.[2] Its ΔpKa/°C is -0.027 and it has a solubility in water at 0°C of 4.2M.

Cholamine chloride hydrochloride
Chemical structure of cholamine chloride hydrochloride
Names
IUPAC name
2-aminoethyl(trimethyl)azanium;chloride;hydrochloride[1]
Other names
Cholamine chloride hydrochloride, Trimethylammoniumchloridehydrochloride
Identifiers
3D model (JSmol)
ChEMBL
ECHA InfoCard 100.020.243
EC Number
  • 222-266-9
  • InChI=1S/C5H15N2.2ClH/c1-7(2,3)5-4-6;;/h4-6H2,1-3H3;2*1H/q+1;;/p-1
    Key: GJBYCNLSIBQCRF-UHFFFAOYSA-M
  • C[N+](C)(C)CCN.Cl.[Cl-]
Properties
C5H16Cl2N2
Molar mass 175.10 g·mol−1
Hazards
GHS labelling:
H315, H319, H335
P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

References
  1. "Cholamine chloride hydrochloride". PharmaCompass. 12 Jul 2007.
  2. "Good's buffers". Protocols Online. 11 Apr 2010.


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