Choline sulfotransferase

In enzymology, a choline sulfotransferase (EC 2.8.2.6) is an enzyme that catalyzes the chemical reaction

3'-phosphoadenylyl sulfate + choline adenosine 3',5'-bisphosphate + choline sulfate
choline sulfotransferase
Identifiers
EC no.2.8.2.6
CAS no.9047-23-8
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

Thus, the two substrates of this enzyme are 3'-phosphoadenylyl sulfate and choline, whereas its two products are adenosine 3',5'-bisphosphate and choline sulfate.[1]

This enzyme belongs to the family of transferases, specifically the sulfotransferases, which transfer sulfur-containing groups. The systematic name of this enzyme class is 3'-phosphoadenylyl-sulfate:choline sulfotransferase. This enzyme is also called choline sulphokinase. This enzyme participates in sulfur metabolism.

References

  1. Orsi BA, Spencer B. "Choline sulphokinase (sulphotransferase)". J. Tokyo. Biochem.: 81–91.


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