Chronotherapy (treatment scheduling)

Chronotherapy, also called chronotherapeutics[1] or chronotherapeutic drug delivery,[2] refers to the coordination of therapeutic treatments with an individual's circadian or other rhythmic cycles. This may be done to maximize effectiveness of a specific treatment, minimize possible side effects, or both.[3][4]

"Chronotherapy" redirects here. For other uses, see Chronotherapy (sleep phase).
Chronotherapy (treatment scheduling)
MeSHD019454

In the treatment of psychiatric conditions including bipolar depression,[5][6] a form of chronotherapy combining intermittent sleep deprivation and morning bright light has shown efficacy and relative tolerability in a number of controlled studies.[7][8][9]

See also

References
  1. "Medical dictionary". Merriam-Webster. Retrieved 6 January 2017.
  2. Sajan J (October 2009). "Chronotherapeutics and Chronotherapeutic Drug Delivery Systems". Tropical Journal of Pharmaceutical Research. 8 (5): 467–475. doi:10.4314/tjpr.v8i5.48091. ISSN 1596-5996. Retrieved 6 January 2017. ...drug availability is timed to match rhythms of disease in order to optimize therapeutic outcomes and minimize side effects.
  3. Dolgin, Elie (1 May 2018). "How to ruin cancer's day". Knowable Magazine. doi:10.1146/knowable-050118-014201. Retrieved 8 August 2022.
  4. Walton, Zandra E.; Altman, Brian J.; Brooks, Rebekah C.; Dang, Chi V. (4 March 2018). "Circadian Clock's Cancer Connections". Annual Review of Cancer Biology. 2 (1): 133–153. doi:10.1146/annurev-cancerbio-030617-050216. ISSN 2472-3428. S2CID 91120424. Retrieved 9 August 2022.
  5. Benedetti F, Barbini B, Fulgosi MC, Colombo C, Dallaspezia S, Pontiggia A, Smeraldi E (December 2005). "Combined total sleep deprivation and light therapy in the treatment of drug-resistant bipolar depression: acute response and long-term remission rates". The Journal of Clinical Psychiatry. 66 (12): 1535–40. doi:10.4088/jcp.v66n1207. PMID 16401154.
  6. Benedetti F, Riccaboni R, Locatelli C, Poletti S, Dallaspezia S, Colombo C (February 2014). "Rapid treatment response of suicidal symptoms to lithium, sleep deprivation, and light therapy (chronotherapeutics) in drug-resistant bipolar depression". The Journal of Clinical Psychiatry. 75 (2): 133–40. doi:10.4088/JCP.13m08455. PMID 24345382.
  7. Benedetti F, Barbini B, Colombo C, Smeraldi E (December 2007). "Chronotherapeutics in a psychiatric ward". Sleep Medicine Reviews. 11 (6): 509–22. doi:10.1016/j.smrv.2007.06.004. PMID 17689120.
  8. Benedetti F (December 2012). "Antidepressant chronotherapeutics for bipolar depression". Dialogues in Clinical Neuroscience. 14 (4): 401–11. doi:10.31887/DCNS.2012.14.4/fbenedetti. PMC 3553570. PMID 23393416.
  9. Dallaspezia S, Suzuki M, Benedetti F (December 2015). "Chronobiological Therapy for Mood Disorders". Current Psychiatry Reports. 17 (12): 95. doi:10.1007/s11920-015-0633-6. PMID 26478195. S2CID 39961490.
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