Cladinose

Cladinose
Names
	IUPAC name (4R,5S,6S)-4-Methoxy-4,6-dimethyl-tetrahydropyran-2,5-diol
Identifiers
CAS Number	470-12-2 ;
3D model (JSmol)	Interactive image;
ChemSpider	391713 ;
PubChem CID	443504;
CompTox Dashboard (EPA)	DTXSID60197001 ;
	InChI InChI=1S/C8H16O4/c1-5-7(10)8(2,11-3)4-6(9)12-5/h5-7,9-10H,4H2,1-3H3/t5-,6?,7-,8+/m0/s1 Key: YHVUVJYEERGYNU-SBEGJHHSSA-N ; InChI=1/C8H16O4/c1-5-7(10)8(2,11-3)4-6(9)12-5/h5-7,9-10H,4H2,1-3H3/t5-,6?,7-,8+/m0/s1 Key: YHVUVJYEERGYNU-SBEGJHHSBA;
	SMILES C[C@H]1[C@@H]([C@](CC(O1)O)(C)OC)O;
Properties
Chemical formula	C8H16O4
Molar mass	176.21 g/mol
Density	1.156 g/mL
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Cladinose is a hexose deoxy sugar that in several antibiotics (such as erythromycin) is attached to the macrolide ring.

In ketolides, a relatively new class of antibiotics, the cladinose is replaced with a keto group.

Erythromycin A with cladinose visible at bottom

External links

Cladinose at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
PubChem
Diagrams

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.