Ibuprofen/paracetamol

Ibuprofen/paracetamol, is a fixed-dose combination of two medications, ibuprofen, a non-steroidal anti-inflammatory drug (NSAID), and paracetamol (acetaminophen).[6] It is available as a generic medication and common brand names include Combiflam.[8][9][10]

Ibuprofen/paracetamol
Combination of
IbuprofenNonsteroidal anti-inflammatory drug
ParacetamolAnalgesic/antipyretic
Clinical data
Trade namesCombiflam, Advil Dual Action with Acetaminophen, Ibupane
Other namesAcetaminophen/ibuprofen
AHFS/Drugs.comMicromedex Detailed Consumer Information
License data
Pregnancy
category
Routes of
administration		By mouth
ATC code
Legal status
Legal status
Identifiers
CAS Number
KEGG

Medical uses

Ibuprofen/paracetamol is indicated for the short term management of mild to moderate acute pain.[7]

There is evidence that paracetamol combined with ibuprofen provides pain relief better than either medication used alone.[11][12]

Adverse effects
See also: Nonsteroidal anti-inflammatory drug § Adverse effects, Ibuprofen § Adverse effects, and Paracetamol § Adverse effects

Society and culture

Brand names

The combination is available as Combiflam,[10][13] Advil Dual Action with Acetaminophen,[14][15][16] Ibupane,[1] and Combogesic.[7]

References
  1. "Ibupane" (PDF). TGA eBS. Archived from the original on 29 October 2020. Retrieved 29 April 2023.
  2. "Nuromol Dual Action Pain Relief 200mg/500mg tablets - Summary of Product Characteristics (SmPC)". (emc). 15 June 2022. Archived from the original on 25 February 2023. Retrieved 24 February 2023.
  3. "Nuromol Pain Relief 200mg/500mg Film Coated Tablets - Summary of Product Characteristics (SmPC)". (emc). 15 June 2022. Archived from the original on 25 February 2023. Retrieved 24 February 2023.
  4. "Nuromol public assessment report". GOV.UK. 16 August 2021. Archived from the original on 25 February 2023. Retrieved 24 February 2023.
  5. "Nuromol Dual Action Pain Relief 200mg/500mg tablets (ibuprofen/paracetamol): public consultation". GOV.UK. 13 May 2021. Archived from the original on 25 February 2023. Retrieved 24 February 2023.
  6. "Advil Dual Action with Acetaminophen- ibuprofen, acetaminophen tablet, film coated". DailyMed. 1 December 2021. Archived from the original on 25 February 2023. Retrieved 25 February 2023.
  7. https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/209471s000lbl.pdf Archived 14 March 2023 at the Wayback Machine
  8. "Competitive Generic Therapy Approvals". U.S. Food and Drug Administration (FDA). 29 June 2023. Archived from the original on 29 June 2023. Retrieved 29 June 2023.
  9. "First Generic Drug Approvals 2023". U.S. Food and Drug Administration (FDA). 30 May 2023. Archived from the original on 30 June 2023. Retrieved 30 June 2023.
  10. "Combiflam". drugs.com. Archived from the original on 5 February 2015. Retrieved 5 February 2015.
  11. Ong CK, Seymour RA, Lirk P, Merry AF (April 2010). "Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain". Anesthesia and Analgesia. 110 (4): 1170–9. doi:10.1213/ANE.0b013e3181cf9281. PMID 20142348. S2CID 7948680.
  12. Moore RA, Derry C (January 2013). "Efficacy of OTC analgesics". International Journal of Clinical Practice. Supplement. 67 (178): 21–5. doi:10.1111/ijcp.12054. PMID 23163544. S2CID 205184492.
  13. "Combiflam". Sanofi India. 28 February 2023. Archived from the original on 3 March 2023. Retrieved 2 March 2023.
  14. "Advil Dual Action: FDA-Approved Drugs". U.S. Food and Drug Administration (FDA). Archived from the original on 26 September 2020. Retrieved 28 February 2020.
  15. "Drug Approval Package: Advil Dual Action with Acetaminophen". U.S. Food and Drug Administration (FDA). 31 March 2020. Archived from the original on 3 March 2023. Retrieved 2 March 2023.
  16. "FDA approves GSK's Advil Dual Action with Acetaminophen for over-the-counter use in the United States" (Press release). GSK Consumer Healthcare. 28 February 2020. Archived from the original on 29 February 2020. Retrieved 28 February 2020 – via PR Newswire.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.