Complement component 6

Complement component 6 is a protein that in humans is encoded by the C6 gene.[5]

C6
Available structures
PDBHuman UniProt search: PDBe RCSB
Identifiers
AliasesC6, complement C6
External IDsOMIM: 217050 MGI: 88233 HomoloGene: 47 GeneCards: C6
Orthologs
SpeciesHumanMouse
Entrez

729

12274

Ensembl

ENSG00000039537

ENSMUSG00000022181

UniProt

P13671

n/a

RefSeq (mRNA)

NM_000065
NM_001115131

NM_016704

RefSeq (protein)

NP_000056
NP_001108603

n/a

Location (UCSC)Chr 5: 41.14 – 41.26 MbChr 15: 4.76 – 4.84 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Complement component 6 is a protein involved in the complement system. It is part of the membrane attack complex which can insert into the cell membrane and cause the cell to lyse.

People with C6 deficiency are prone to bacterial infection.[5]

References

  1. GRCh38: Ensembl release 89: ENSG00000039537 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000022181 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: complement component 6 C6 complement C6 (Homo sapiens (human)) Gene ID: 729". www.ncbi.nlm.nih.gov. 24 November 2020. Retrieved 9 December 2020.

Further reading


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