Cosimo Commisso (scientist)

Cosimo Commisso is a Canadian cell biologist and cancer researcher who has made significant advances in the field of cellular trafficking and cancer metabolism.[1][2][3] Among his most notable contributions are the discovery and study of how macropinocytosis supports tumor cell growth and survival by serving as an amino acid supply route in Ras-mutated cancers.[4][5][6] He is currently an associate professor in the Tumor Initiation and Maintenance Program at the Sanford Burnham Prebys Medical Discovery Institute NCI-designated Cancer Center in La Jolla, California, USA.

For the Canadian soccer player with the same name, see Cosimo Commisso (soccer). For the criminal with the same name, see Cosimo Commisso (mobster).

References
  1. Trading, American Laboratory. "DR. COSIMO COMMISSO AND THE NUTRIENT SCAVENGERS". americanlaboratorytrading.com. Retrieved 2017-11-20.
  2. "2015 Grant Recipient Cosimo Commisso, PhD – Pancreatic Cancer Action Network". Pancreatic Cancer Action Network. Retrieved 2017-11-20.
  3. Action, Pancreatic Cancer (2013-05-27). "New understanding of nutrient uptake in Pancreatic Cancer cells could lead to future drug targets · Pancreatic Cancer Action". Pancreatic Cancer Action. Retrieved 2017-11-20.
  4. Commisso, Cosimo; Davidson, Shawn M.; Soydaner-Azeloglu, Rengin G.; Parker, Seth J.; Kamphorst, Jurre J.; Hackett, Sean; Grabocka, Elda; Nofal, Michel; Drebin, Jeffrey A. (2013-05-12). "Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells". Nature. 497 (7451): 633–637. doi:10.1038/nature12138. ISSN 1476-4687. PMC 3810415. PMID 23665962.
  5. Kamphorst, Jurre J.; Nofal, Michel; Commisso, Cosimo; Hackett, Sean R.; Lu, Wenyun; Grabocka, Elda; Vander Heiden, Matthew G.; Miller, George; Drebin, Jeffrey A. (2015-02-01). "Human Pancreatic Cancer Tumors Are Nutrient Poor and Tumor Cells Actively Scavenge Extracellular Protein". Cancer Research. 75 (3): 544–553. doi:10.1158/0008-5472.can-14-2211. PMC 4316379. PMID 25644265.
  6. Commisso, Cosimo; Flinn, Rory J; Bar-Sagi, Dafna (2014-01-02). "Determining the macropinocytic index of cells through a quantitative image-based assay". Nature Protocols. 9 (1): 182–192. doi:10.1038/nprot.2014.004. ISSN 1750-2799. PMC 4103788. PMID 24385148.
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