Cucurbitin

Cucurbitin is an amino acid and a carboxypyrrolidine that is found in Cucurbita seeds.[1][2] Cucurbitin causes degenerative changes in the reproductive organs of parasitic flatworms called flukes.[3][4]

Cucurbitin
Names
Preferred IUPAC name
(3R)-3-Aminopyrrolidine-3-carboxylic acid
Other names
(+)-Cucurbitin; Cucurbitine
Identifiers
3D model (JSmol)
ChemSpider
UNII
  • InChI=1S/C5H10N2O2/c6-5(4(8)9)1-2-7-3-5/h7H,1-3,6H2,(H,8,9)/t5-/m1/s1
    Key: DWAKXSZUASEUHH-RXMQYKEDSA-N
  • InChI=1/C5H10N2O2/c6-5(4(8)9)1-2-7-3-5/h7H,1-3,6H2,(H,8,9)/t5-/m1/s1
    Key: DWAKXSZUASEUHH-RXMQYKEDBI
  • O=C(O)[C@]1(N)CNCC1
Properties
C5H10N2O2
Molar mass 130.147 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

References
  1. "Pumpkin". Drugs.com. Retrieved November 22, 2014.
  2. Mihranian, Valentine H; Abou-Chaar, Charles I (1968). "Extraction, detection, and estimation of cucurbitin in Cucurbita seeds". Lloydia. 31 (1): 23–29.
  3. Annual Reports in Medicinal Chemistry, Cornelius Kennedy Cain, 1966, Academic Press, ISBN 0120405016
  4. Austin, Daniel F. (2004). Florida Ethnobotany. Boca Raton, Florida: CRC Press. pp. 411–412. ISBN 978-0-8493-2332-4.


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