Dopachrome tautomerase

Dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2), also known as DCT, is a human gene.[5] Its expression is regulated by the microphthalmia-associated transcription factor (MITF).[6][7]

DCT
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesDCT, TRP-2, TYRP2, dopachrome tautomerase, OCA8
External IDsOMIM: 191275 MGI: 102563 HomoloGene: 1447 GeneCards: DCT
Orthologs
SpeciesHumanMouse
Entrez

1638

13190

Ensembl

ENSG00000080166

ENSMUSG00000022129

UniProt

P40126

P29812

RefSeq (mRNA)

NM_010024

RefSeq (protein)

NP_034154

Location (UCSC)Chr 13: 94.44 – 94.48 MbChr 14: 118.25 – 118.29 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

See also

References

  1. GRCh38: Ensembl release 89: ENSG00000080166 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000022129 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: DCT dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2)".
  6. Yasumoto K, Takeda K, Saito H, et al. (2002). "Microphthalmia-associated transcription factor interacts with LEF-1, a mediator of Wnt signaling". EMBO J. 21 (11): 2703–14. doi:10.1093/emboj/21.11.2703. PMC 126018. PMID 12032083.
  7. Hoek KS, Schlegel NC, Eichhoff OM, et al. (2008). "Novel MITF targets identified using a two-step DNA microarray strategy". Pigment Cell Melanoma Res. 21 (6): 665–76. doi:10.1111/j.1755-148X.2008.00505.x. PMID 19067971.

Further reading

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