dTDP-L-rhamnose 4-epimerase

DTDP-L-rhamnose 4-epimerase (EC 5.1.3.25, dTDP-4-L-rhamnose 4-epimerase, wbiB (gene)) is an enzyme with systematic name dTDP-6-deoxy-beta-L-talose 4-epimerase.[1] This enzyme catalyses the following chemical reaction

dTDP-6-deoxy-beta-L-talose dTDP-6-deoxy-beta-L-mannose
DTDP-L-rhamnose 4-epimerase
Identifiers
EC no.5.1.3.25
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

The equilibrium is strongly towards dTDP-6-deoxy-beta-L-mannose.

References

  1. Yoo HG, Kwon SY, Karki S, Kwon HJ (July 2011). "A new route to dTDP-6-deoxy-l-talose and dTDP-L-rhamnose: dTDP-L-rhamnose 4-epimerase in Burkholderia thailandensis". Bioorganic & Medicinal Chemistry Letters. 21 (13): 3914–7. doi:10.1016/j.bmcl.2011.05.030. PMID 21640586.
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