Delta6-protoilludene synthase
Δ6-Protoilludene synthase (EC 4.2.3.135, 6-protoilludene synthase) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, Δ6-protoilludene-forming).[1] This enzyme catalyses the following chemical reaction
- (2E,6E)-farnesyl diphosphate Δ6-protoilludene + diphosphate
| Δ6-protoilludene synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 4.2.3.135 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
This enzyme is isolated from the fungus Armillaria gallica.
References
- Engels B, Heinig U, Grothe T, Stadler M, Jennewein S (2011). "Cloning and characterization of an Armillaria gallica cDNA encoding protoilludene synthase, which catalyzes the first committed step in the synthesis of antimicrobial melleolides". J. Biol. Chem. 286 (9): 6871–6878. doi:10.1074/jbc.m110.165845. PMC 3044942. PMID 21148562.
External links
- Delta6-protoilludene+synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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