Dinitolmide

Dinitolmide (or zoalene) is a fodder additive for poultry, used to prevent coccidiosis infections.[2] It is sold under trade names such as Coccidine A, Coccidot, and Zoamix.

Dinitolmide
Names
Preferred IUPAC name
2-Methyl-3,5-dinitrobenzamide
Other names
3,5-Dinitro-o-toluamide
Zoalene
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.005.189
UNII
  • InChI=1S/C8H7N3O5/c1-4-6(8(9)12)2-5(10(13)14)3-7(4)11(15)16/h2-3H,1H3,(H2,9,12) checkY
    Key: ZEFNOZRLAWVAQF-UHFFFAOYSA-N checkY
  • InChI=1/C8H7N3O5/c1-4-6(8(9)12)2-5(10(13)14)3-7(4)11(15)16/h2-3H,1H3,(H2,9,12)
    Key: ZEFNOZRLAWVAQF-UHFFFAOYAL
  • O=[N+]([O-])c1cc(cc(C(=O)N)c1C)[N+]([O-])=O
Properties
C8H7N3O5
Molar mass 225.16 g/mol
Melting point 177 °C; 351 °F; 450 K[1]
Pharmacology
QP51AX12 (WHO)
Hazards
Flash point noncombustible[1]
NIOSH (US health exposure limits):
PEL (Permissible)
 none[1]
REL (Recommended)
 TWA 5 mg/m3[1]
IDLH (Immediate danger)
 N.D.[1]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)
Infobox references

Dinitolmide is usually added to feed in doses of 125 ppm (preventive) or 250 ppm (curative). It is a broad-spectrum anticoccidial drug,[2] preventing seven main strains of Eimeria coccidium. It leaves no residues in tissues. It can be also used to prevent coccidiosis of domestic rabbits.

References
  1. NIOSH Pocket Guide to Chemical Hazards. "#0230". National Institute for Occupational Safety and Health (NIOSH).
  2. Gerhold, R. W.; Fuller, A. L.; Lollis, L.; Parr, C.; McDougald, L. R. (2011). "The Efficacy of Anticoccidial Products against Eimeria spp. in Northern Bobwhites". Avian Diseases. 55 (1): 59–64. doi:10.1637/9572-101310-Reg.1. PMID 21500637. S2CID 30943649.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.