Dishevelled binding antagonist of beta catenin 2
Dishevelled binding antagonist of beta catenin 2 is a protein that in humans is encoded by the DACT2 gene. [5]
| DACT2 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Aliases | DACT2, C6orf116, DAPPER2, DPR2, bA503C24.7, dishevelled binding antagonist of beta catenin 2 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 608966 MGI: 1920347 HomoloGene: 18237 GeneCards: DACT2 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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References
- GRCh38: Ensembl release 89: ENSG00000164488 - Ensembl, May 2017
- GRCm38: Ensembl release 89: ENSMUSG00000048826 - Ensembl, May 2017
- "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Entrez Gene: Dishevelled binding antagonist of beta catenin 2". Retrieved 2017-09-10.
Further reading
- Koga Y, Yao T, Hirahashi M, Kumashiro Y, Ohji Y, Yamada T, Tanaka M, Tsuneyoshi M (2008). "Flat adenoma-carcinoma sequence with high-malignancy potential as demonstrated by CD10 and beta-catenin expression: a different pathway from the polypoid adenoma-carcinoma sequence". Histopathology. 52 (5): 569–77. doi:10.1111/j.1365-2559.2008.02996.x. PMID 18370954. S2CID 26122361.
- Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR (2010). "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score". Mol. Med. 16 (7–8): 247–53. doi:10.2119/molmed.2009.00159. PMC 2896464. PMID 20379614.
- Hendrickson SL, Lautenberger JA, Chinn LW, Malasky M, Sezgin E, Kingsley LA, Goedert JJ, Kirk GD, Gomperts ED, Buchbinder SP, Troyer JL, O'Brien SJ (2010). "Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression". PLOS ONE. 5 (9): e12862. Bibcode:2010PLoSO...512862H. doi:10.1371/journal.pone.0012862. PMC 2943476. PMID 20877624.
- Jia Y, Yang Y, Brock MV, Zhan Q, Herman JG, Guo M (2013). "Epigenetic regulation of DACT2, a key component of the Wnt signalling pathway in human lung cancer". J. Pathol. 230 (2): 194–204. doi:10.1002/path.4073. PMC 4061565. PMID 22806826.
- Cheng H, Lu M, Mao LJ, Wang JQ, Li W, Wen RM, Chen JC (2012). "Relationships among MTHFR a1298c gene polymorphisms and methylation status of Dact1 gene in transitional cell carcinomas". Asian Pac. J. Cancer Prev. 13 (10): 5069–74. doi:10.7314/apjcp.2012.13.10.5069. PMID 23244112.
- Zhang X, Yang Y, Liu X, Herman JG, Brock MV, Licchesi JD, Yue W, Pei X, Guo M (2013). "Epigenetic regulation of the Wnt signaling inhibitor DACT2 in human hepatocellular carcinoma". Epigenetics. 8 (4): 373–82. doi:10.4161/epi.24113. PMC 3674046. PMID 23449122.
- Gao S, Yang Z, Zheng ZY, Yao J, Zhang F, Wu LM, Xie HY, Zhou L, Zheng SS (2013). "Reduced expression of DACT2 promotes hepatocellular carcinoma progression: involvement of methylation-mediated gene silencing". World J Surg Oncol. 11: 57. doi:10.1186/1477-7819-11-57. PMC 3605395. PMID 23496880.
- Hou J, Liao LD, Xie YM, Zeng FM, Ji X, Chen B, Li LY, Zhu MX, Yang CX, Qing-Zhao, Chen T, Xu XE, Shen J, Guo MZ, Li EM, Xu LY (2013). "DACT2 is a candidate tumor suppressor and prognostic marker in esophageal squamous cell carcinoma". Cancer Prev Res (Phila). 6 (8): 791–800. doi:10.1158/1940-6207.CAPR-12-0352. PMID 23803417.
- Wang S, Dong Y, Zhang Y, Wang X, Xu L, Yang S, Li X, Dong H, Xu L, Su L, Ng SS, Chang Z, Sung JJ, Zhang X, Yu J (2015). "DACT2 is a functional tumor suppressor through inhibiting Wnt/β-catenin pathway and associated with poor survival in colon cancer". Oncogene. 34 (20): 2575–85. doi:10.1038/onc.2014.201. PMC 4761644. PMID 25023701.
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