Diterpene alkaloids

Diterpene alkaloids are natural products of the terpene alkaloid type.[1]

Garrya veatchii
Aconitum napellus

Occurrence

Veatchine is found in the bark of Garrya veatchii, a member of the Cup Catkins family.[2] Aconitine is the main alkaloid in aconite.[3]

Structure

Diterpene alkaloids can be divided into two groups: The diterpene alkaloids, characterized by a C20 parent body, and the norditerpene alkaloids, which are based on a hexacyclic C19 parent body.[1]

Representatives

Diterpene group

Among the C20 alkaloids is the atisine-type (atisine, hetidine, hetisine) and the veatchine-type (Veatchin, Napellin).[1]

  • Atisine
    Atisine
  • Veatchin
    Veatchin

Northern iterpene group

The C19 alkaloids include, among others, the aconitine type (aconitine, delphinine) and the lycoctonine type (Lycoctonin, Browniin).[1]

  • (+)-Lycoctonine
    (+)-Lycoctonine

Properties

Aconitine has cardiac arrhythmic and antipyretic properties and is one of the most toxic plant compounds.[2]

References
  1. Entry on Diterpen-Alkaloide. at: Römpp Online. Georg Thieme Verlag, retrieved {{{Datum}}}.
  2. Eberhard Breitmaier (1997), Alkaloide, Wiesbaden: Springer Fachmedien, pp. 83f., ISBN 9783519035428
  3. Rudolf Hänsel, Otto Sticher (2007), Pharmakognosie Phytopharmazie (8 ed.), Heidelberg: Springer Medizin Verlag, p. 1466, ISBN 9783540265085
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