E-site

The E-site is the third and final binding site for t-RNA in the ribosome during translation, a part of protein synthesis.[1] The "E" stands for exit, and is accompanied by the P-site (for peptidyl) which is the second binding site, and the A-site (aminoacyl), which is the first binding site. It is involved in cellular processes. [2]

References

  1. Chen, C.; Stevens, B.; Kaur, J.; Smilansky, Z.; Cooperman, B. S.; Goldman, Y. E. (2011-10-03). "Allosteric vs. spontaneous exit-site (E-site) tRNA dissociation early in protein synthesis". Proceedings of the National Academy of Sciences. 108 (41): 16980–16985. Bibcode:2011PNAS..10816980C. doi:10.1073/pnas.1106999108. ISSN 0027-8424. PMC 3193197. PMID 21969541.
  2. Kirillov, S., Makarov, E., & Semenkov, Y. (1983). Quantitative study of interaction of deacylated tRNA with Escherichia coli ribosomes. FEBS Letters, 157(1), 91-94. doi:10.1016/0014-5793(83)81122-3
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