ELAV-like protein 2

ELAVL2
Identifiers
Aliases	ELAVL2, HEL-N1, HELN1, HUB, ELAV like neuron-specific RNA binding protein 2, ELAV like RNA binding protein 2
External IDs	OMIM: 601673 MGI: 1100887 HomoloGene: 20930 GeneCards: ELAVL2
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)[1]
End	91,400,785 bp[1]
RNA expression pattern
	n/a
	Top expressed in
	superior cervical ganglion; ; facial motor nucleus; ; mammillary body; ; medial ganglionic eminence; ; medial dorsal nucleus; ; medial vestibular nucleus; ; lateral hypothalamus; ; pontine nuclei; ; dorsomedial hypothalamic nucleus; ; ventral tegmental area;
	More reference expression data
Gene ontology
Molecular function	protein binding; mRNA 3'-UTR binding; nucleic acid binding; RNA binding;
Cellular component	nucleoplasm;
Biological process	regulation of transcription, DNA-templated; mRNA splicing, via spliceosome;
	Sources:Amigo / QuickGO
Orthologs
	1993
	15569
	ENSG00000107105
	ENSMUSG00000008489
	Q12926
	Q60899
	NM_001171195; NM_001171197; NM_004432
NM_001177883; NM_010486; NM_207685; NM_207686; NM_001347149;
	NM_001357188; NM_001357189
NP_001164666; NP_001164668; NP_004423; NP_001338384; NP_001338385;
	NP_001338386; NP_001338387; NP_001338388; NP_001338389; NP_001338390; NP_001338391; NP_001338392; NP_001338393; NP_001338394; NP_001338395; NP_001338396; NP_001338397; NP_001338398; NP_001338399; NP_001338400; NP_001338401; NP_001338402; NP_001338403; NP_001338404; NP_001338405; NP_001338406; NP_001338407
NP_001171354; NP_001334078; NP_034616; NP_997568; NP_997569;
	NP_001344117; NP_001344118; NP_001361165; NP_001361166; NP_001361167; NP_001361625
	Wikidata
View/Edit Human	View/Edit Mouse

ELAV-like protein 2 is a protein that in humans is encoded by the ELAVL2 gene.[4][5]

References

GRCm38: Ensembl release 89: ENSMUSG00000008489 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Han J, Knops JF, Longshore JW, King PH (Feb 1997). "Localization of human elav-like neuronal protein 1 (Hel-N1) on chromosome 9p21 by chromosome microdissection polymerase chain reaction and fluorescence in situ hybridization". Genomics. 36 (1): 189–91. doi:10.1006/geno.1996.0444. PMID 8812435.
"Entrez Gene: ELAVL2 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)".

Gao FB, Carson CC, Levine T, Keene JD (1994). "Selection of a subset of mRNAs from combinatorial 3' untranslated region libraries using neuronal RNA-binding protein Hel-N1". Proc. Natl. Acad. Sci. U.S.A. 91 (23): 11207–11. Bibcode:1994PNAS...9111207G. doi:10.1073/pnas.91.23.11207. PMC 45196. PMID 7972035.
King PH, Levine TD, Fremeau RT, Keene JD (1994). "Mammalian homologs of Drosophila ELAV localized to a neuronal subset can bind in vitro to the 3' UTR of mRNA encoding the Id transcriptional repressor". J. Neurosci. 14 (4): 1943–52. doi:10.1523/JNEUROSCI.14-04-01943.1994. PMC 6577146. PMID 8158249.
Gao FB, Keene JD (1997). "Hel-N1/Hel-N2 proteins are bound to poly(A)+ mRNA in granular RNP structures and are implicated in neuronal differentiation". J. Cell Sci. 109 (3): 579–89. doi:10.1242/jcs.109.3.579. PMID 8907704.
Park S, Myszka DG, Yu M, et al. (2000). "HuD RNA recognition motifs play distinct roles in the formation of a stable complex with AU-rich RNA". Mol. Cell. Biol. 20 (13): 4765–72. doi:10.1128/MCB.20.13.4765-4772.2000. PMC 85909. PMID 10848602.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9". Nature. 429 (6990): 369–74. Bibcode:2004Natur.429..369H. doi:10.1038/nature02465. PMC 2734081. PMID 15164053.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Yano M, Okano HJ, Okano H (2005). "Involvement of Hu and heterogeneous nuclear ribonucleoprotein K in neuronal differentiation through p21 mRNA post-transcriptional regulation". J. Biol. Chem. 280 (13): 12690–9. doi:10.1074/jbc.M411119200. PMID 15671036.

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[refGRCm38Ensembl-1] GRCm38: Ensembl release 89: ENSMUSG00000008489 - Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8812435-4] Han J, Knops JF, Longshore JW, King PH (Feb 1997). "Localization of human elav-like neuronal protein 1 (Hel-N1) on chromosome 9p21 by chromosome microdissection polymerase chain reaction and fluorescence in situ hybridization". Genomics. 36 (1): 189–91. doi:10.1006/geno.1996.0444. PMID 8812435.

[entrez-5] "Entrez Gene: ELAVL2 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)".

ELAV-like protein 2

References

Further reading