ELP2

Elongator complex protein 2 is a protein that in humans is encoded by the ELP2 gene.[5][6][7]

ELP2
Identifiers
AliasesELP2, SHINC-2, STATIP1, StIP, elongator acetyltransferase complex subunit 2, MRT58
External IDsOMIM: 616054 MGI: 1889642 HomoloGene: 6019 GeneCards: ELP2
Orthologs
SpeciesHumanMouse
Entrez

55250

58523

Ensembl

ENSG00000134759

ENSMUSG00000024271

UniProt

Q6IA86

Q91WG4

RefSeq (mRNA)

NM_021448
NM_001360909

RefSeq (protein)

NP_067423
NP_001347838

Location (UCSC)Chr 18: 36.13 – 36.18 MbChr 18: 24.74 – 24.77 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse


Interactions

ELP2 has been shown to interact with STAT3[6] and Janus kinase 1.[6]

References

  1. GRCh38: Ensembl release 89: ENSG00000134759 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000024271 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Hawkes NA, Otero G, Winkler GS, Marshall N, Dahmus ME, Krappmann D, Scheidereit C, Thomas CL, Schiavo G, Erdjument-Bromage H, Tempst P, Svejstrup JQ (Jan 2002). "Purification and characterization of the human elongator complex". J Biol Chem. 277 (4): 3047–52. doi:10.1074/jbc.M110445200. PMID 11714725.
  6. Collum RG, Brutsaert S, Lee G, Schindler C (Oct 2000). "A Stat3-interacting protein (StIP1) regulates cytokine signal transduction". Proc Natl Acad Sci U S A. 97 (18): 10120–5. doi:10.1073/pnas.170192197. PMC 27739. PMID 10954736.
  7. "Entrez Gene: STATIP1 signal transducer and activator of transcription 3 interacting protein 1".

Further reading


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