Edifenphos

Edifenphos (O-ethyl-S,S-diphenyldithiophosphate, EDDP) is a systemic fungicide that inhibits phosphatidylcholine biosynthesis.[2][3] It was introduced in 1966 by Bayer to combat blast fungus and Pellicularia sasakii in rice cultivation.[3] It was never authorized for use in the EU.[4]

Edifenphos
Names
Preferred IUPAC name
O-Ethyl S,S-diphenyl phosphorodithioate
Other names
O-Ethyl-S,S-diphenyldithiophosphate; EDDP
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.037.420
KEGG
UNII
  • InChI=1S/C14H15O2PS2/c1-2-16-17(15,18-13-9-5-3-6-10-13)19-14-11-7-4-8-12-14/h3-12H,2H2,1H3
    Key: AWZOLILCOUMRDG-UHFFFAOYSA-N
  • CCOP(=O)(Sc1ccccc1)Sc2ccccc2
Properties
C14H15O2PS2
Molar mass 310.37 g·mol−1
Density 1.23  g/cm3[1]
Melting point −25 °C (−13 °F; 248 K)[1]
56 mg/L (20 °C)[1]
Hazards
GHS labelling:
GHS06: ToxicGHS09: Environmental hazard[1]
Danger
H301, H311, H317, H331, H410[1]
P261, P273, P280, P301+P310, P311, P501[1]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

References
  1. Record of Edifenphos in the GESTIS Substance Database of the Institute for Occupational Safety and Health, accessed on 2016-02-01.
  2. Kodama, Osamu; Yamashita, Kenji; Akatsuka, Tadami (1980). "Edifenphos, Inhibitor of Phosphatidylcholine Biosynthesis in Pyricularia oryzae". Agricultural and Biological Chemistry. 44 (5): 1015–1021. doi:10.1080/00021369.1980.10864095.
  3. Matolcsy, György; Nádasy, Miklós; Andriska, Viktor; Terényi, Sándor (1989). Pesticide Chemistry. Elsevier. p. 306. ISBN 978-0444989031.
  4. "Edifenphos: Not Approved". EU Pesticides Database Active Substances. Retrieved 2016-02-01.
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