Eleanor Dare

John Smith and other members of the Jamestown Colony sought information about the fate of the colonists in 1607. One report indicated that the Lost Colonists took refuge with friendly Chesapeake Indians, but Chief Powhatan claimed his tribe had attacked the group and killed most of the colonists. Powhatan showed Smith certain artifacts he said had belonged to the colonists, including a musket barrel and a brass mortar. The Jamestown Colony received reports of some survivors of the Lost Colony and sent out search parties, but none was successful. Eventually they determined that the early colonists had all died.[2]

But, in her 2000 book Roanoke: Solving the Mystery of the Lost Colony (2000), Miller postulated that some of the Lost Colony survivors sought shelter with a neighboring Indian tribe, the Chowanoc. This group was attacked by another tribe, identified by the Jamestown Colony as the "Mandoag." Miller thinks these were the Eno, also known as the Wainoke. Survivors were eventually sold into slavery and held captive by differing bands of the Eno tribe, who, Miller wrote, were known slave traders. Miller wrote that English settlers with the Jamestown Colony heard reports in 1609 of the captive Englishmen, but the reports were suppressed because they had no way to rescue the captives and didn't want to panic the Jamestown colonists.

William Strachey, a secretary of the Jamestown Colony, wrote in his The History of Travel Into Virginia Britania (1612) that, at the Indian settlements of Peccarecanick and Ochanahoen, there were reportedly two-story houses with stone walls,built in the English fashion. The Indians supposedly learned how to build them from the Roanoke settlers.[3] There were also reported sightings of European captives at various Indian settlements during the same time period.[4] Strachey wrote in 1612 that four English men, two boys, and one girl had been sighted at the Eno settlement of Ritanoc, under the protection of a chief called Eyanoco. The captives were forced to beat copper. The captives, he reported, had escaped the attack on the other colonists and fled up the Choanoke river, the present-day Chowan River in Bertie County, North Carolina.[3][5]

The Chowanoc tribe was eventually absorbed into the Tuscarora. The Eno tribe was also associated with the Shakori tribe and was later absorbed by the Catawba or the Saponi tribes. From the early 17th century to the middle 18th century, European colonists reported encounters with gray-eyed American Indians or with Welsh-speaking Indians who claimed descent from the colonists.[6] In 1669 a Welsh cleric named Morgan Jones was taken captive by the Tuscarora. He feared for his life, but a visiting Doeg Indian war captain spoke to him in Welsh and assured him that he would not be killed. The Doeg warrior ransomed Jones and his party and Jones remained with their tribe for months as a preacher.[7] In 1701, surveyor John Lawson encountered members of the Hatteras tribe living on Roanoke Island who claimed some of their ancestors were white people. Lawson wrote that several of the Hatteras tribesmen had gray eyes.[8] Some present-day American Indian tribes in North Carolina and South Carolina, among them the Coree and the Lumbee, also claim partial descent from surviving Roanoke colonists. A non-profit organization, the Lost Colony Center for Science and Research, has launched a Lost Colony DNA Project to test possible descendants.