Emily Leproust

Emily Leproust is an American scientist and entrepreneur. She is the CEO and co-founder[1] of Twist Bioscience, a public company working on DNA synthesis. The company harnesses synthetic biology, providing tools to manufacture insulin from yeast, to tackle malaria,[2] produce spider silk at scale[3] or store information on DNA.[4][5] She was awarded the BIO Rosalind Franklin Award in 2020.[6]

Education and career

Leproust earned an M.Sc. in Industrial Chemistry from the Lyon School of Industrial Chemistry[7] in 1995 and a PhD in Organic Chemistry & Nucleic Acids Chemistry from the University of Houston in 2001.[8] She worked for the company Agilent where she was Director of Applications and Chemistry R&D—Genomics before starting the company Twist Bioscience.

Leproust participated in a March 2021 tabletop exercise at the Munich Security Conference simulating an outbreak of weaponized monkeypox.[9]

Publications
  • Gnirke A, Melnikov A, Maguire J, Rogov P, LeProust EM, Brockman W, Fennell T, Giannoukos G, Fisher S, Russ C, Gabriel S. Solution hybrid selection with ultra-long oligonucleotides for massively parallel targeted sequencing. Nature biotechnology. 2009 Feb;27(2):182-9.
  • Kaplan N, Moore IK, Fondufe-Mittendorf Y, Gossett AJ, Tillo D, Field Y, LeProust EM, Hughes TR, Lieb JD, Widom J, Segal E. The DNA-encoded nucleosome organization of a eukaryotic genome. Nature. 2009 Mar;458(7236):362-6.
  • Goldman N, Bertone P, Chen S, Dessimoz C, LeProust EM, Sipos B, Birney E. Towards practical, high-capacity, low-maintenance information storage in synthesized DNA. Nature. 2013 Feb;494(7435):77-80.

References
  1. RFS Briefings - September 30, 2020 Rosalind Franklin society
  2. How Twist Bioscience is writing the future of sustainability. – TED
  3. How DNA synthesis is powering the fourth manufacturing revolution - SynBioBeta Podcast, with Emily Leproust
  4. Goldman, Nick; Bertone, Paul; Chen, Siyuan; Dessimoz, Christophe; LeProust, Emily M.; Sipos, Botond; Birney, Ewan (February 2013). "Towards practical, high-capacity, low-maintenance information storage in synthesized DNA". Nature. 494 (7435): 77–80. Bibcode:2013Natur.494...77G. doi:10.1038/nature11875. PMC 3672958. PMID 23354052.
  5. Vitak, Sarah (3 March 2021). "Technology alliance boosts efforts to store data in DNA". Nature. doi:10.1038/d41586-021-00534-w. PMID 33658669. S2CID 232112632.
  6. "BIO Announces 2020 BIO IMPACT Award Winners" (Press release). BIO. 17 September 2020.
  7. Sitting down with Emily Leproust, CEO, Twist Bioscience – Drug Discovery World
  8. Asking All the Right Questions: Emily Leproust (’01), Top Global Thinker – University of Houston
  9. Yassif, Jaime; O'Prey, Kevin; Isaac, Christopher (November 2021). "Strengthening Global Systems to Prevent and Respond to High-Consequence Biological Threats" (PDF). Nuclear Threat Initiative. Archived (PDF) from the original on 2022-07-09. Retrieved 2022-07-09.


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