Encapsulating peritoneal sclerosis

Encapsulating peritoneal sclerosis (EPS) is a medical condition that causes the encapsulation of feces within a thickened fibrocollagenous peritoneal membrane, which leads to recurrent episodes of bowel obstruction. It is a rare serious complication typically caused by peritoneal dialysis.[1][2][3] It is usually seen as a late complication of peritoneal dialysis (PD), occurring in those who have been receiving peritoneal dialysis for more than 5 years. It is associated with a high morbidity.[4] In one study, the cumulative incidence of EPS in those undergoing peritoneal dialysis was 0.3%, 0.8% and 3.9% at 3, 5 and 8 years respectively with no increase in mortality when compared to those undergoing PD without EPS.[5]

References
  1. Mihalache, O.; Bugă, C.; Doran, H.; Catrina, E.; Bobircă, F.; Pătrașcu, T. (2014). "Encapsulating Peritoneal Sclerosis – A rare and serious complication of peritoneal dialysis: Case series". Journal of Medicine and Life. 7 (Spec Iss 3): 8–12. PMC 4391411. PMID 25870687.
  2. Singhal, M.; Krishna, S.; Lal, A.; Narayanasamy, S.; Bal, A.; Yadav, T. D.; Kochhar, R.; Sinha, S. K.; Khandelwal, N.; Sheikh, A. M. (2019). "Encapsulating Peritoneal Sclerosis: The Abdominal Cocoon". RadioGraphics. 39 (1): 62–77. doi:10.1148/rg.2019180108. PMID 30526331.
  3. Danford, C. J.; Lin, S. C.; Smith, M. P.; Wolf, J. L. (2018). "Encapsulating peritoneal sclerosis". World Journal of Gastroenterology. 24 (28): 3101–3111. doi:10.3748/wjg.v24.i28.3101. PMC 6064970. PMID 30065556.
  4. Teitelbaum, Isaac (4 November 2021). "Peritoneal Dialysis". New England Journal of Medicine. 385 (19): 1786–1795. doi:10.1056/NEJMra2100152.
  5. Johnson, David W.; Cho, Yeoungjee; Livingston, Brian E.R.; Hawley, Carmel M.; McDonald, Stephen P.; Brown, Fiona G.; Rosman, Johan B.; Bannister, Kym M.; Wiggins, Kathryn J. (May 2010). "Encapsulating peritoneal sclerosis: incidence, predictors, and outcomes". Kidney International. 77 (10): 904–912. doi:10.1038/ki.2010.16.


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