Ent-pimara-9(11),15-diene synthase

ent-Pimara-9(11),15-diene synthase (EC 4.2.3.31, PMD synthase) is an enzyme with systematic name ent-copalyl-diphosphate diphosphate-lyase (ent-pimara-9(11),15-diene-forming).[1] This enzyme catalyses the following chemical reaction

ent-copalyl diphosphate ent-pimara-9(11),15-diene + diphosphate
ent-pimara-9(11),15-diene synthase
Identifiers
EC no.4.2.3.31
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

This enzyme is involved in the biosynthesis of the diterpenoid viguiepinol and requires Mg2+, Co2+, Zn2+ or Ni2+ for activity.

References

  1. Ikeda C, Hayashi Y, Itoh N, Seto H, Dairi T (January 2007). "Functional analysis of eubacterial ent-copalyl diphosphate synthase and pimara-9(11),15-diene synthase with unique primary sequences". Journal of Biochemistry. 141 (1): 37–45. doi:10.1093/jb/mvm004. PMID 17148547.


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