Epi-cedrol synthase

epi-Cedrol synthase (EC 4.2.3.39, 8-epicedrol synthase, epicedrol synthase) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (8-epi-cedrol-forming).[1][2] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate + H2O 8-epi-cedrol + diphosphate
epi-cedrol synthase
Identifiers
EC no.4.2.3.39
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

This enzyme is activated by Mg2+.

References

  1. Mercke P, Crock J, Croteau R, Brodelius PE (September 1999). "Cloning, expression, and characterization of epi-cedrol synthase, a sesquiterpene cyclase from Artemisia annua L". Archives of Biochemistry and Biophysics. 369 (2): 213–22. doi:10.1006/abbi.1999.1358. PMID 10486140.
  2. Hua L, Matsuda SP (September 1999). "The molecular cloning of 8-epicedrol synthase from Artemisia annua". Archives of Biochemistry and Biophysics. 369 (2): 208–12. doi:10.1006/abbi.1999.1357. PMID 10486139.


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