Erik van Nimwegen

Erik van Nimwegen (born 5 November 1970 in Amsterdam, Netherlands) is a Dutch computational biologist and Professor at the Biozentrum of the University of Basel, Switzerland. [1]

Erik van Nimwegen
Erik van Nimwegen (2015)
Born (1970-11-05) 5 November 1970
Amsterdam
NationalityDutch
Scientific career
FieldsComputational Biology
InstitutionsUniversity of Amsterdam, Santa Fe Institute, Utrecht University, Rockefeller University, Swiss Institute of Bioinformatics, Biozentrum University of Basel


Life

Erik van Nimwegen studied theoretical physics at the University of Amsterdam. He performed his PhD studies at the Santa Fe Institute (SFI) in Santa Fe New Mexico, receiving his PhD from the Faculty of Biology at Utrecht University in 1999. This was followed by a year of post-doc studies at the SFI, and three years as a fellow at the Center of Studies in Physics and Biology at the Rockefeller University, New York. Since 2003 he is Professor of Computational Biology at the Biozentrum of the University of Basel,[2] and group leader at the Swiss Institute of Bioinformatics since 2004.[3]

Work

Erik van Nimwegen’s main research topics concern genome evolution and the function and evolution of the regulatory networks by which cells control gene expression.[4][5] He develops mathematical models for analyzing how regulatory networks evolve and function, and computational methods for the reconstruction of such networks from large biological data-sets. Van Nimwegen's work includes a general model for the evolution of robustness against mutations and the identification of a number of universal scaling laws of genome evolution.[6] Further research topics are the development of general Bayesian methods for transcription factor and miRNA binding site prediction as well as models for inferring regulatory networks from genome-wide expression and chromatin state data.[7]

Awards and honors

Since 2010 Member of the editorial board of the journal PLoS Computational Biology.[8]

References
  1. "Erik van Nimwegen". simons.berkeley.edu. Retrieved 2023-09-19.
  2. "Curriculum Vitae". Biozentrum.unibas.ch. Retrieved 2014-06-24.
  3. "SIB Group E. van Nimwegen". isb-sib.ch. Retrieved 2014-04-28.
  4. Balwierz, Piotr J.; Pachkov, Mikhail; Arnold, Phil; Gruber, Andreas J.; Zavolan, Mihaela; Van Nimwegen, Erik (2014). "ISMARA: Automated modeling of genomic signals as a democracy of regulatory motifs". Genome Research. genome.cshlp.org. 24 (5): 869–884. doi:10.1101/gr.169508.113. PMC 4009616. PMID 24515121. Retrieved 2014-04-28.
  5. Wolf, Luise; Silander, Olin K.; Van Nimwegen, Erik J. (2014). "Expression noise facilitates the evolution of gene regulation". biorxiv.org: 007237. doi:10.1101/007237. S2CID 196682469. Retrieved 2020-08-03. {{cite journal}}: Cite journal requires |journal= (help)
  6. Van Nimwegen, E.; Crutchfield, J. P.; Huynen, M. (1999). "Neutral evolution of mutational robustness". Proceedings of the National Academy of Sciences. pnas.org. 96 (17): 9716–9720. arXiv:adap-org/9903006. Bibcode:1999PNAS...96.9716V. doi:10.1073/pnas.96.17.9716. PMC 22276. PMID 10449760.
  7. Balwierz, P. J.; Pachkov, M.; Arnold, P.; Gruber, A. J.; Zavolan, M.; Van Nimwegen, E. (2014). "ISMARA: automated modeling of genomic signals as a democracy of regulatory motifs". Genome Research. nih.gov. 24 (5): 869–884. doi:10.1101/gr.169508.113. PMC 4009616. PMID 24515121.
  8. "PLOS Computational Biology Editorial Board". ploscompbiol.org. Retrieved 2014-04-28.
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