Exosome component 4

Exosome component 4, also known as EXOSC4, is a human gene, which is part of the exosome complex.[5]

EXOSC4
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesEXOSC4, RRP41, RRP41A, Rrp41p, SKI6, Ski6p, hRrp41p, p12A, Exosome component 4
External IDsOMIM: 606491 MGI: 1923576 HomoloGene: 6017 GeneCards: EXOSC4
Orthologs
SpeciesHumanMouse
Entrez

54512

109075

Ensembl

ENSG00000178896

ENSMUSG00000034259

UniProt

Q9NPD3

Q921I9

RefSeq (mRNA)

NM_019037

NM_175399

RefSeq (protein)

NP_061910

NP_780608

Location (UCSC)Chr 8: 144.08 – 144.08 MbChr 15: 76.21 – 76.21 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

Exosome component 4 has been shown to interact with Exosome component 2.[6]

References

  1. GRCh38: Ensembl release 89: ENSG00000178896 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000034259 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: EXOSC4 exosome component 4".
  6. Raijmakers R, Egberts WV, van Venrooij WJ, Pruijn GJ (2002). "Protein-protein interactions between human exosome components support the assembly of RNase PH-type subunits into a six-membered PNPase-like ring". J. Mol. Biol. 323 (4): 653–63. doi:10.1016/S0022-2836(02)00947-6. PMID 12419256.

Further reading


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