FCHSD2

FCH and double SH3 domains protein 2 is a protein that in humans is encoded by the FCHSD2 gene.[5][6][7]

FCHSD2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesFCHSD2, NWK, SH3MD3, FCH and double SH3 domains 2, NWK1
External IDsOMIM: 617556 MGI: 2448475 HomoloGene: 8887 GeneCards: FCHSD2
Orthologs
SpeciesHumanMouse
Entrez

9873

207278

Ensembl

ENSG00000137478

ENSMUSG00000030691

UniProt

O94868

Q3USJ8

RefSeq (mRNA)

NM_014824

NM_001146010
NM_199012

RefSeq (protein)

NP_055639

NP_001139482
NP_950177

Location (UCSC)Chr 11: 72.84 – 73.14 MbChr 7: 100.74 – 100.93 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

FCHSD2 has been shown to interact with MAGI1[8] and C2orf73.[9]

References

  1. GRCh38: Ensembl release 89: ENSG00000137478 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000030691 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Nagase T, Ishikawa K, Suyama M, Kikuno R, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (October 1998). "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Research. 5 (5): 277–86. doi:10.1093/dnares/5.5.277. PMID 9872452.
  6. Katoh M, Katoh M (May 2004). "Identification and characterization of human FCHSD1 and FCHSD2 genes in silico". International Journal of Molecular Medicine. 13 (5): 749–54. doi:10.3892/ijmm.13.5.749. PMID 15067381.
  7. "Entrez Gene: FCHSD2 FCH and double SH3 domains 2".
  8. Ohno H, Hirabayashi S, Kansaku A, Yao I, Tajima M, Nishimura W, Ohnishi H, Mashima H, Fujita T, Omata M, Hata Y (November 2003). "Carom: a novel membrane-associated guanylate kinase-interacting protein with two SH3 domains". Oncogene. 22 (52): 8422–31. doi:10.1038/sj.onc.1206996. PMID 14627983.
  9. Thalappilly S, Suliman M, Gayet O, Soubeyran P, Hermant A, Lecine P, Iovanna JL, Dusetti NJ (August 2008). "Identification of multi-SH3 domain-containing protein interactome in pancreatic cancer: a yeast two-hybrid approach". Proteomics. 8 (15): 3071–81. doi:10.1002/pmic.200701157. PMID 18654987. S2CID 25344443.

Further reading

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