FIZ1
FLT3 interacting zinc finger 1 is a protein that in humans is encoded by the FIZ1 gene. [5]
| FIZ1 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| Aliases | FIZ1, ZNF798, FLT3 interacting zinc finger 1 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 609133 MGI: 1344336 HomoloGene: 22663 GeneCards: FIZ1 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Function
This gene encodes zinc finger protein, which interacts with a receptor tyrosine kinase involved in the regulation of hematopoietic and lymphoid cells. This gene product also interacts with a transcription factor that regulates the expression of rod-specific genes in retina. [provided by RefSeq, Jul 2008].
References
- GRCh38: Ensembl release 89: ENSG00000179943 - Ensembl, May 2017
- GRCm38: Ensembl release 89: ENSMUSG00000061374 - Ensembl, May 2017
- "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Entrez Gene: FLT3 interacting zinc finger 1". Retrieved 2018-05-22.
Further reading
- Mitton KP, Swain PK, Khanna H, Dowd M, Apel IJ, Swaroop A (February 2003). "Interaction of retinal bZIP transcription factor NRL with Flt3-interacting zinc-finger protein Fiz1: possible role of Fiz1 as a transcriptional repressor". Hum. Mol. Genet. 12 (4): 365–73. doi:10.1093/hmg/ddg035. PMID 12566383.
- Mali RS, Zhang X, Hoerauf W, Doyle D, Devitt J, Loffreda-Wren J, Mitton KP (February 2007). "FIZ1 is expressed during photoreceptor maturation, and synergizes with NRL and CRX at rod-specific promoters in vitro". Exp. Eye Res. 84 (2): 349–60. doi:10.1016/j.exer.2006.10.009. PMC 5066392. PMID 17141759.
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