FLRT2

Fibronectin leucine-rich repeat transmembrane protein FLRT2 is a protein that in humans is encoded by the FLRT2 gene.[5][6][7]

FLRT2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesFLRT2, fibronectin leucine rich transmembrane protein 2
External IDsOMIM: 604807 MGI: 3603594 HomoloGene: 8291 GeneCards: FLRT2
Orthologs
SpeciesHumanMouse
Entrez

23768

399558

Ensembl

ENSG00000185070

ENSMUSG00000047414

UniProt

O43155

Q8BLU0

RefSeq (mRNA)

NM_001346143
NM_001346144
NM_001346145
NM_001346146
NM_013231

NM_201518

RefSeq (protein)

NP_001333072
NP_001333073
NP_001333074
NP_001333075
NP_037363

NP_958926

Location (UCSC)Chr 14: 85.53 – 85.65 MbChr 12: 95.66 – 95.75 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

This gene encodes a member of the fibronectin leucine rich transmembrane protein (FLRT) family. FLRT family members may function in cell adhesion and/or receptor signalling. Their protein structures resemble small leucine-rich proteoglycans found in the extracellular matrix.[7]

References

  1. GRCh38: Ensembl release 89: ENSG00000185070 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000047414 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Lacy SE, Bönnemann CG, Buzney EA, Kunkel LM (December 1999). "Identification of FLRT1, FLRT2, and FLRT3: a novel family of transmembrane leucine-rich repeat proteins". Genomics. 62 (3): 417–26. doi:10.1006/geno.1999.6033. PMID 10644439.
  6. Haines BP, Wheldon LM, Summerbell D, Heath JK, Rigby PW (September 2006). "Regulated expression of FLRT genes implies a functional role in the regulation of FGF signalling during mouse development". Developmental Biology. 297 (1): 14–25. doi:10.1016/j.ydbio.2006.04.004. PMID 16872596.
  7. "Entrez Gene: FLRT2 fibronectin leucine rich transmembrane protein 2".

Further reading

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.