Fakhreddin Jamali

Fakhreddin Jamali (born May 31, 1945) is an Iranian-Canadian professor emeritus of pharmacy and pharmaceutical sciences at the University of Alberta. He is the founding president of the Canadian Society for Pharmaceutical Sciences,[2] and the editor-in-chief of Journal of Pharmacy and Pharmaceutical Sciences.[3]

Fakhreddin Jamali
Born (1945-05-31) May 31, 1945
Arak, Iran
EducationUniversity of British Columbia (PhD)
University of Tehran (Pharm.D.)
Known forfounding the Canadian Society for Pharmaceutical Sciences
Spouse(s)Elaheh Keshavarz-Jamali, PharmD, PhD (b. 1945- d. 2020) [1]
ChildrenVafa Jamali[1]
AwardsAlberta Centennial Medal, AAPS fellowship, CSPS fellowship, Killam Professorship
Scientific career
Fieldspharmaceutical sciences
InstitutionsUniversity of Alberta

Early life

Fakhreddin was born May 31, 1945, in Arak, Iran to Jamaleddin Jamali and Batoul Rouhani-Jamali.[4][5]

Career

Jamali's focus has been on drugs action (pharmacodynamics) and disposition (pharmacokinetics) particularly in field of analgesics and antiinfammatory therapy. His earlier work on the stereoselective and stereospecific therapeutic and toxicity of drugs received high peer recognition.[6] He also reported that pain and/or its trauma delays absorption of drugs which may render them ineffective.[7] This is particularly important when a quick action is desired such as pain relief. His group found that inflammatory conditions such as arthritis diminish response to some cardiovascular drugs despite already known increased circulatory concentrations.[8] His group also has reported the mechanism behind the adverse cardiovascular effects of both anti-inflammatory drugs and inflammatory conditions.[9][10] Jamali has received many national and international awards for his contribution to science and public wellbeing.[11]

References
  1. "Dr. Fakhreddin Jamali: Pharmacist, Pharmaceutical Scientist and Mentor".
  2. "2018 Board of Directors". Cspscanada.org. Retrieved 17 January 2019.
  3. "Editorial Team". Journals.library.ualberta.ca. Retrieved 12 August 2018.
  4. "سخنرانی دکتر فخرالدین جمالی در دانشکده داروسازی". Tehran University of Medical Sciences. Retrieved 26 January 2019.
  5. "کانون سردفتران و دفتریاران". www.notary.ir. Retrieved 26 January 2019.
  6. Jamali, F.; Mehvar, R.; Pasutto, F. M. (1 September 1989). "Enantioselective Aspects of Drug Action and Disposition: Therapeutic Pitfalls". Journal of Pharmaceutical Sciences. 78 (9): 695–715. doi:10.1002/jps.2600780902. ISSN 0022-3549. PMID 2685226.
  7. Jamali, Fakhreddin; Kunz-Dober, Cornelia M. (April 1999). "Pain-mediated altered absorption and metabolism of ibuprofen: an explanation for decreased serum enantiomer concentration after dental surgery: Pain-mediated altered absorption of ibuprofen". British Journal of Clinical Pharmacology. 47 (4): 391–396. doi:10.1046/j.1365-2125.1999.00902.x. PMC 2014238. PMID 10233203.
  8. Abdallah, Yasmeen El Hajj; Chahal, Sukhman; Jamali, Fakhreddin; Mahmoud, Sherif Hanafy (2023). "Drug-disease interaction: Clinical consequences of inflammation on drugs action and disposition". Journal of Pharmacy & Pharmaceutical Sciences. 26: 11137. doi:10.3389/jpps.2023.11137. ISSN 1482-1826. PMC 9990632. PMID 36942294.
  9. Aghazadeh-Habashi, Ali; Asghar, Waheed; Jamali, Fakhreddin (1 February 2018). "Drug-Disease Interaction: Effect of Inflammation and Nonsteroidal Anti-Inflammatory Drugs on Cytochrome P450 Metabolites of Arachidonic Acid". Journal of Pharmaceutical Sciences. 107 (2): 756–763. doi:10.1016/j.xphs.2017.09.020. ISSN 0022-3549. PMID 28989019.
  10. Asghar, Waheed; Aghazadeh-Habashi, Ali; Jamali, Fakhreddin (1 October 2017). "Cardiovascular effect of inflammation and nonsteroidal anti-inflammatory drugs on renin–angiotensin system in experimental arthritis". Inflammopharmacology. 25 (5): 543–553. doi:10.1007/s10787-017-0344-1. ISSN 1568-5608. PMID 28389995. S2CID 254576802.
  11. "Fakhreddin Jamali". International Pharmaceutical Federation.


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