Fat atypical cadherin 3

FAT3
Identifiers
Aliases	FAT3, CDHF15, CDHR10, hFat3, FAT atypical cadherin 3
External IDs	OMIM: 612483 MGI: 2444314 HomoloGene: 82252 GeneCards: FAT3
Gene location (Human)
Chr.	Chromosome 11 (human)[1]
End	92,896,473 bp[1]
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)[2]
End	16,412,581 bp[2]
RNA expression pattern
	Top expressed in
	Brodmann area 23; ; middle temporal gyrus; ; endothelial cell; ; external globus pallidus; ; tibia; ; parietal lobe; ; entorhinal cortex; ; postcentral gyrus; ; Brodmann area 46; ; superior frontal gyrus;
	Top expressed in
	habenula; ; olfactory tubercle; ; median eminence; ; vas deferens; ; body of femur; ; mammillary body; ; globus pallidus; ; substantia nigra; ; superior colliculus; ; primary motor cortex;
	More reference expression data
	n/a
Gene ontology
Molecular function	calcium ion binding;
Cellular component	integral component of membrane; plasma membrane; membrane;
Biological process	homophilic cell adhesion via plasma membrane adhesion molecules; multicellular organism development; cell adhesion; cell-cell adhesion;
	Sources:Amigo / QuickGO
Orthologs
	120114
	270120
	ENSG00000165323
	ENSMUSG00000074505
	Q8TDW7
	Q8BNA6
	NM_001008781; NM_001367949; NM_001378141
	NM_001080814
	NP_001008781; NP_001354878; NP_001365070
	NP_001074283
	Wikidata
View/Edit Human	View/Edit Mouse

FAT atypical cadherin 3 is a protein that in humans is encoded by the FAT3 gene.[5]

References

GRCh38: Ensembl release 89: ENSG00000165323 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000074505 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Entrez Gene: FAT atypical cadherin 3".

Berndt JD, Aoyagi A, Yang P, Anastas JN, Tang L, Moon RT (September 2011). "Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/β-catenin signaling". The Journal of Cell Biology. 194 (5): 737–50. doi:10.1083/jcb.201107021. PMC 3171123. PMID 21875946.
Zheng JS, Arnett DK, Lee YC, Shen J, Parnell LD, Smith CE, Richardson K, Li D, Borecki IB, Ordovás JM, Lai CQ (2013). "Genome-wide contribution of genotype by environment interaction to variation of diabetes-related traits". PLOS ONE. 8 (10): e77442. Bibcode:2013PLoSO...877442Z. doi:10.1371/journal.pone.0077442. PMC 3810463. PMID 24204828.
Mitsui K, Nakajima D, Ohara O, Nakayama M (February 2002). "Mammalian fat3: a large protein that contains multiple cadherin and EGF-like motifs". Biochemical and Biophysical Research Communications. 290 (4): 1260–6. doi:10.1006/bbrc.2002.6338. PMID 11811999.
Wu Q (April 2005). "Comparative genomics and diversifying selection of the clustered vertebrate protocadherin genes". Genetics. 169 (4): 2179–88. doi:10.1534/genetics.104.037606. PMC 1449604. PMID 15744052.

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