Flavin adenine dinucleotide synthetase 1

FLAD1
Identifiers
Aliases	FLAD1, FAD1, FADS, PP591, flavin adenine dinucleotide synthetase 1, LSMFLAD
External IDs	OMIM: 610595 MGI: 2443030 HomoloGene: 115598 GeneCards: FLAD1
Gene location (Human)
Chr.	Chromosome 1 (human)[1]
End	154,993,111 bp[1]
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)[2]
End	89,411,870 bp[2]
RNA expression pattern
	Top expressed in
	skin of abdomen; ; gastrocnemius muscle; ; right lobe of thyroid gland; ; right lobe of liver; ; ganglionic eminence; ; body of stomach; ; left lobe of thyroid gland; ; left ventricle; ; spleen; ; right uterine tube;
	Top expressed in
	interventricular septum; ; extraocular muscle; ; left lobe of liver; ; digastric muscle; ; temporal muscle; ; sternocleidomastoid muscle; ; triceps brachii muscle; ; right ventricle; ; brown adipose tissue; ; myocardium of ventricle;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity; nucleotide binding; nucleotidyltransferase activity; protein binding; catalytic activity; ATP binding; FMN adenylyltransferase activity;
Cellular component	mitochondrial matrix; plasma membrane; mitochondrion; cytoplasm; cytosol;
Biological process	riboflavin metabolic process; metabolism; FAD biosynthetic process;
	Sources:Amigo / QuickGO
Orthologs
	80308
	319945
	ENSG00000160688
	ENSMUSG00000042642
	Q8NFF5
	Q8R123
	NM_001184891; NM_001184892; NM_025207; NM_201398
	NM_177041
	NP_001171820; NP_001171821; NP_079483; NP_958800
	NP_796015; NP_001349304; NP_001349305
	Wikidata
View/Edit Human	View/Edit Mouse

Flavin adenine dinucleotide synthetase 1 is a protein that in humans is encoded by the FLAD1 gene. [5]

Function

This gene encodes the enzyme that catalyzes adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

References

GRCh38: Ensembl release 89: ENSG00000160688 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000042642 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Entrez Gene: Flavin adenine dinucleotide synthetase 1". Retrieved 2016-03-04.

Flavin adenine dinucleotide synthetase 1

Function

References

Further reading